Results 121 to 130 of about 2,700,270 (309)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Student Chamber Music Recital, February 27, 1991 [PDF]

open access: yes, 1991
This is the concert program of the Student Chamber Music Recital on Thursday, February 27, 1991 at 6:30 p.m., at the Marshall Room, 855 Commonwealth Avenue. Works performed were Canzona personare No. 4 by Giovanni Gabrieli, I. Allegro from String Quartet
School of Music, Boston University
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Impact of New York City’s 4-year multi-component natural experiment to improve elementary school physical education on student cardiorespiratory fitness

open access: yesBMC Public Health
Background School physical education is an important population-level health intervention for improving youth fitness. This study estimated the impact of New York City’s PE Works program - which included providing PE teachers, training for classroom ...
Hannah R. Thompson   +4 more
doaj   +1 more source

Fearless Friday: Erin Meachem

open access: yes, 2016
In this round of Fearless Friday, SURGE is honoring the work of Erin Meachem ‘16! Erin is originally from Queensbury, New York and is currently in her senior year at Gettysburg, majoring in English and Spanish.
Meachem, Erin M.
core  

String Department Student Concert, November 30, 1994 [PDF]

open access: yes, 1994
This is the concert program of the String Department Student Concert performance on Wednesday, November 30, 1994 at 8:00 p.m., at the Marshall Room, 855 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Whalesong [PDF]

open access: yes, 2004
Services meet students' special needs -- Safety report good news -- Democracy done right -- Post-Thanksgiving puzzle -- Free-flowing talent show entertains -- When finals reign -- What is your Christmas personality? -- No fun?

core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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