Results 101 to 110 of about 162,716 (314)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Wits Architecture Student Works 1922-1980; Lennard MD 1947 B Arch V. A Furniture Factory Sketch Design; Proposed Guest House, Lakeside View, Stand no 274, Northmere, B Arch II first term, 1947

, 2014
Wits Architecture Student Works 1922-1980; Lennard, MD 1947-1950; Furniture Factory; Proposed Guest House LakesideViewWits Architecture Student Works 1922-1980; Lennard, MD 1947-1950; Furniture Factory; Proposed Guest House ...
Lennard, MD
core  

The potential for using gamification in academic libraries in order to increase student engagement and achievement

, 2014
This paper discusses the potential benefits of using gamification techniques to increase student engagement with library resources. It outlines the link between student use of library resources and academic achievement, and suggests that gamification has
Walsh, Andrew, Andrew Walsh
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Wits Architecture Student Works 1922-1980. Sutton, Michael. Colour Chart Sheet no 5 BArch I 1951; Conventional Presentation (Cape Dutch Home) Sheet no 7 BArch I 1951; Greek Architecture BArch II 1952

, 2014
Wits Architecture Student Works 1922-1980. Sutton, Michael. Colour Chart Sheet no 5 BArch I 1951; Conventional Presentation (Cape Dutch Home) Sheet no 7 BArch I 1951; Greek Architecture BArch II 1952.
Sutton, Michael
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Wits Architecture Student Works 1922-1980. Moross, H 1942. Presentation Drawings for a Family Residence : Design Subject. B Arch II; 1941. Study of the Greek Doric Order. B Arch I.

, 2014
Wits Architecture Student Works 1922-1980; Moross, H. 1941 B Arch 1st year Study of the Greek Doric Order; 1942 B Arch 2nd year. Presentation Drawings for a Family Residence: Design Subject.Wits Architecture Student Works 1922-1980; Moross, H.
Moross, H
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Wits Architecture Student Works 1922-1980. Radomsky, H. 1933. A Residential Group for a College, ground floor plan, drawing I; A Residential Group for a College, drawing II. BArch IV.

, 2014
Wits Architecture Student Works 1922-1980. Radomsky, H. 1933. A Residential Group for a College, ground floor plan, drawing I; A Residential Group for a College, drawing II. BArch IVWits Architecture Student Works 1922-1980. Radomsky, H. 1933.
Radomsky, H
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source