β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
International students' experiences on speaking and writing skills in language learning processes in higher education. [PDF]
Karakuş İ.
europepmc +1 more source
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
Transformative learning through the "Honor Walk" in nursing education: a qualitative study. [PDF]
Shen MY, Feng ZX, Jin JW, Liu FC.
europepmc +1 more source
Strategies to improve academic motivation in undergraduate nursing students in Iran: a qualitative content analysis. [PDF]
Afshar MT+5 more
europepmc +1 more source
From classroom to clinic: a qualitative study of gendered experiences among nursing students and educators in Türkiye. [PDF]
Olgay SŞ+3 more
europepmc +1 more source
Variation in Students' Experiences and Approaches to Learning During Early Clinical Immersion. [PDF]
Staples N+6 more
europepmc +1 more source
The role of fear of intimacy and loneliness in predicting of academic enthusiasm in medical science students: a cross-sectional study from the Iran. [PDF]
Asadi MR+7 more
europepmc +1 more source
Meaningful youth engagement in sexual and reproductive health and rights decision making
Klaudia Szymuś+7 more
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