Results 61 to 70 of about 15,365,324 (324)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Short Communications: Basic Sciences

open access: yesRUHS Journal of Health Sciences, 2023
Postgraduate Students
doaj   +1 more source

The Great Water Hook-up [PDF]

open access: yes
In this activity students assume the role of water system designers. They have been asked to go to a small town to design a new public water supply system. They must decide how to link all the homes and businesses to the water source so that everyone can

core   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Short Communications: Para Clinical Sciences

open access: yesRUHS Journal of Health Sciences, 2023
Postgraduate Students
doaj   +1 more source

A Wetland Field Study [PDF]

open access: yes
The field projects at this site give students an opportunity to investigate a number of wetland characteristics firsthand: surveying wetland vegetation, soils, water quality and wildlife; documenting the wetland from an artist's perspective ...

core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Short Communications: Clinical Sciences

open access: yesRUHS Journal of Health Sciences, 2023
Postgraduate Students
doaj   +1 more source

DIFFERENTIATE FACTORS OF PREGNANT WOMEN WITH CHRONIC ENERGY DEFICIENCY OCCURRENCE IN BAJULMATI VILLAGE, WONGSOREJO DISTRICT, BANYUWANGI REGENCY 2019

open access: yesJournal of Community Medicine and Public Health Research, 2020
Riskesdas result in 2013 showed that the prevalence of WUS population who were pregnant and at risk of CED was 24,2%. CED in pregnant women can cause abortion and premature birth, low birth weight babies and infant disability, children become ...
Bisyamsi Nawaijaya Moediarso   +13 more
doaj   +1 more source

How Much Water Do You Use? [PDF]

open access: yes
This activity is designed to make students aware of how much water individuals and families use on a weekly basis. They will analyze their family's water use with a focus on ways to reduce consumption. Students conduct the survey at home for a full week.

core   +1 more source

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