Results 151 to 160 of about 77,951 (273)

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

open access: yesAdvanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang   +19 more
wiley   +1 more source

Teacher stress among Tawjihi teachers in Jordan and their adopted coping strategies to reduce stress

open access: yes
There has been increasing interest in occupational stress during the last two decades. While studies have been carried out in developed countries, few have been conducted in developing countries, particularly in the field of education.
Alghaswyneh, Sawsan A I
core  

Examining the Professional Learning and Development of Principals and Teachers in Maori Medium.

open access: yes, 2013
The Resource Teacher Māori service (RTM) has been working to lift the performance of principals and teachers of Māori medium schools for over 25 years as Māori medium education has attempted to achieve the twofold aim of revitalizing the Māori language ...
McClunie, Adrienne Heeni
core  

Preparing teachers to cooperate with parents

open access: yesMultidisciplinary Journal of School Education
Research objectives (aims) and problem(s): Cooperation between teachers and parents is one of the fundamental tasks of the school. It is closely related to the idea of the subjectivity of the family and school in the education process, which is based on
Anna Królikowska
doaj  

A medical student in private practice for a 1-month clerkship: a qualitative exploration of the challenges for primary care clinical teachers

open access: yesAdvances in Medical Education and Practice, 2017
Virginie Muller-Juge, Anne Catherine Pereira Miozzari, Arabelle Rieder, Jennifer Hasselgård-Rowe, Johanna Sommer, Marie-Claude Audétat Unit of Primary Care, Faculty of Medicine, University of Geneva, Geneva ...
Muller-Juge V   +5 more
doaj  

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

open access: yesAdvanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao   +13 more
wiley   +1 more source

Cult on the rise? Students' perspectives on cult issues in secondary and national high schools in Papua New Guinea

open access: yes, 2008
In the last five years there has been a dramatic increase in perceived levels of antisocial behaviour amongst students in Secondary and National High schools in Papua New Guinea. Certain events have caught the public's attention, such as the burning down
Drawii, Judy Tatu
core  

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

open access: yesAdvanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu   +11 more
wiley   +1 more source

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