Results 151 to 160 of about 9,718,538 (338)

Birth Order and Education: Evidence from a Korean Cohort [PDF]

This paper estimates the effects of birth order on education. This paper is the first to control for the mother’s age at first birth. While previous studies find that earlier-born children are better off, this paper finds no effects.Birth order ...
Cho, Hyunkuk
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Good luck have fun: The need for video game pedagogy in teacher education

Future in Educational Research
In education, the shift to emergency remote teaching found teachers working to increase student engagement in the online environment while still relying on face‐to‐face pedagogical approaches in the absence of sufficient Professional Development ...
Tasha Richardson
doaj   +1 more source

Bullying victimization and mental health before and during the COVID-19 pandemic

Frontiers in Child and Adolescent Psychiatry
IntroductionBullying victimization is associated with numerous mental health difficulties yet studies from early in the COVID-19 pandemic revealed significant decreases in bullying victimization but significant increases in mental health difficulties for
Ann H. Farrell, Heather Brittain, Amanda Krygsman, Tracy Vaillancourt, Tracy Vaillancourt   +4 more
doaj   +1 more source

Picturing Teacher Agency: Developing Upstanding Heuristics in a Middle Grades Social Studies Methods Course [PDF]

, 2019
This paper presents a multi-case study of teacher candidates in a pre-service middle grades social studies methods course. The research aimed to understand how the middle grades teacher candidates viewed their future as upstanders with agency in middle ...
Farley, Jennifer, Gallagher, Jennifer L
core   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

COVID-19 Post-Pandemic Adaptation and Resilience: A Cross-Cultural Study of China and Canada

COVID
The COVID-19 pandemic altered individuals’ worldviews. This study examined how cultural values shaped the ways students navigated stress and adapted after the COVID-19 pandemic.
Sarah-Mei Chen, Junru Yan, Fan Yang, Clara B. Rebello, Angelie M. Ignacio, Chao S. Hu, Gerald C. Cupchik   +6 more
doaj   +1 more source

Addressing contemporary ethical and moral issues through islamic education

Journal on Islamic Studies
This research aims to explore how Islamic education addresses contemporary ethical and moral issues and informs ethical discourse and practice in educational contexts.
Molina Ibrahim, Shahidullah Islam, Okundaye Zohriah, Menezes Azid   +3 more
semanticscholar   +1 more source

A Prison of Education: The School-to-Prison Pipeline in Low-Income Schools [PDF]

, 2016
This paper examines the relationship between prisons and education in American culture, comparing public schools in California cities to wealthier private schools.
Le, Adam
core   +1 more source