Results 61 to 70 of about 622,021 (312)

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Validation of the extended version of the Implementation Leadership Scale (ILS-X)

Implementation Science Communications
Background Implementation science has made significant advances in our understanding of organizational factors that impact the implementation process.
Mark G. Ehrhart, Nathaniel J. Williams, Marisa Sklar, Nallely R. Vega, Alexandra Kandah, Gregory A. Aarons   +5 more
doaj   +1 more source

Genetic and Environmental Sources of Nomophobia: A Small-Scale Turkish Twin Study

Addicta: The Turkish Journal on Addictions, 2019
Nomophobia is considered to be a form of behavioral addiction, namely the fear of being out of mobile phone contact. Despite many studies on the prevalence and correlates of mobile phone addiction, not much is known about its etiological nature.
Deniz Deryakulu, Ömer Faruk Ursavaş
doaj   +1 more source

Gaming addiction, definition, and measurement: a large-scale empirical study [PDF]

, 2013
Aims: Although the general public appears to have embraced the term 'video game addiction', the scientific debate as to whether 'gaming addiction' can actually be considered an addiction similar to substance addictions of DSM-IV is still unsettled. To
Griffiths, MD, Konijn, EA, Roelofsma, PHMP, Spekman, MLC   +3 more
core   +1 more source

Required sample size to detect mediation in 3-level implementation studies

Implementation Science, 2022
Background Statistical tests of mediation are important for advancing implementation science; however, little research has examined the sample sizes needed to detect mediation in 3-level designs (e.g., organization, provider, patient) that are common in ...
Nathaniel J. Williams, Kristopher J. Preacher, Paul D. Allison, David S. Mandell, Steven C. Marcus   +4 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

ANCOVA Study of Psychotherapy Treatment of Internet Pornography Addiction in Heterosexual Men [PDF]

, 2015
Internet pornography has grown to become a problem that exists within the United States and across the globe. For those who suffer from this problematic behavior experience individual and familial problems as well as cause damage to the psyche ...
Twine, Saudia L
core   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Testing normalization process theory in a randomized trial of mental health clinics implementing digital measurement-based care

Implementation Science
Background Normalization process theory (NPT) is one of the most highly cited implementation theories that explains the mechanisms by which new complex health interventions become embedded and sustained in healthcare settings; however, few of its ...
Nathaniel J. Williams, Mimi Choy-Brown, Nallely Vega, Gregory A. Aarons, Mark G. Ehrhart, Steven C. Marcus   +5 more
doaj   +1 more source