Results 201 to 210 of about 52,751,136 (335)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Design of a Pressure Sensitive Cell and Model Studies of Pressures in the Subgrade of a Flexible Pavement System : Technical Paper

, 1960
Thurmul McMahon, Eldon Yoder
openalex   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Multidomain intervention for delaying aging in community-dwelling older adults (MIDA): study design and protocol. [PDF]

Ann Med
Lin S, Wang F, Huang M, Chen J, Jiang X, Li Q, Yuan Y, Huang F, Zhu P.   +8 more
europepmc   +1 more source

Core Design Study for a 500MWe Fast Oxide Reactor

, 1961
K.M. Horst, B.A. Hutchins, F.J. Leitz, B. Wolfe   +3 more
openalex   +2 more sources

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Interoccasion variability in population pharmacokinetic models: identifiability, influence, interdependencies and derived study design recommendations. [PDF]

J Pharmacokinet Pharmacodyn
Behrens E, Wicha SG.
europepmc   +1 more source

DESIGN STUDIES OF PROTON LINEAR ACCELERATORS

, 1963
D. E. Young, R. S. Christian, C. Curtis, Thomas W. D. Edwards, F. J. Kriegler, F.E. Mills, P. Morton, D.A. Swenson, J. Van Bladel   +8 more
openalex   +2 more sources

Discussion: “Studies of the Design of Steel Castings and Steel Weldments as Related to Methods of Their Manufacture” (Nara, Harry R., Wright, Jr., D. K., and Briggs, Charles W., 1961, ASME J. Eng. Ind., 83, pp. 73–91) [PDF]

, 1961
Jeff Wallace
openalex   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source