Results 131 to 140 of about 4,398,549 (286)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

PERSEPSI GURU PEMBIMBING TERHADAP PROSES PEMBELAJARAN MAHASISWA PRAKTIK PPL UNIVERSITAS NEGERI YOGYAKARTA DI SMK PIRI 1 YOGYAKARTA TAHUN AJARAN 2012/2013 [PDF]

open access: yes, 2012
This study aims to describe perception of tutor to student skills practice in the implementation of the learning process PPL SMK Piri 1 Yogyakarta in the academic year 2012/2013.
Niken Ayu, Larasati
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Understanding e-book usage: using citation analysis to inform study skills teaching [PDF]

open access: yes, 2014
To deliver effective information literacy teaching, an accurate understanding of user behaviour is vital. The increasing availability and use of e-books will impact upon student information seeking behaviour.
Groves, Antony
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Relationship between Students’ Study Skills and Academic Achievement [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2013
Introduction: One of the factors affecting academic achievement is study skills therefore, we aimed at determining the relationship between study skills and students’ academic achievement in Golestan University of Medical Sciences.
Mohamad taghi Badele shamooshaki   +4 more
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Skills Training in Laboratory and Clerkship: Connections, Similarities, and Differences [PDF]

open access: yes, 2003
Context: During the third semester of a 6 year long curriculum medical students train clinical skills in the skills laboratory (2 hours per week for 9 weeks) as well as in an early, 8 week clinical clerkship at county hospitals.
Eika , M.D., Ph.D., Berit   +3 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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