Results 111 to 120 of about 9,213,332 (293)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Study on Multiaxial Fatigue Damage Behavior of HRB335 Under Variable-Amplitude and Variable-Path Loading

open access: yesBuildings
Fatigue failure is a prevalent concern within structural engineering, often resulting in critical safety risks. The inherent complexity of construction projects leads to structural components experiencing loads of varying amplitudes and diverse load ...
Shihong Huang   +2 more
doaj   +1 more source

Study on Failure Boundary of Thermal-scuffing for Heavy Duty Gear Transmission with Variable Speed and Variable Torsion

open access: yesJixie chuandong, 2021
In view of the service characteristics of driving devices such as construction machinery, aerospace, rail transit and electric vehicle in the variable speed and variable torsion, the damage mechanism of thermal-scuffing failure for gear transmission is ...
Jiqiang Li   +5 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Experimental Study on Variable-frequency Screw Compressor with Economizer under Variable Working Conditions

open access: yesZhileng xuebao, 2018
To improve the efficiency of a variable-frequency screw compressor with an economizer, the effect of parameters such as the discharge pressure of the compressor, motor frequency, injection pressure of the economizer, and volumetric efficiency on the ...
Qin Huanghui
doaj  

The application of propensity score methods in observational studies

open access: yesFrontiers in Applied Mathematics and Statistics
IntroductionIn research, it is crucial to accurately estimate treatment effects and analyze experimental results. Common methods include comparing outcome differences between different groups and using linear regression models for analysis.
Yuejuan Zhao
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Mechanical optimization of plate-screw interfaces in variable-angle locking systems: a parametric study

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionVariable-angle locking systems offer increased surgical flexibility by permitting off-axis screw insertion, with some designs allowing angulation up to 15°.
Chen-Chiang Lin   +5 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

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