Results 81 to 90 of about 7,746 (198)

Integrative Modular, Network‐Based, and Machine Learning Framework for Predicting Accessory Genome Functions and Virulence in Escherichia coli O157:H7

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
An analysis of the accessory genomes from 77 Escherichia coli O157:H7 strains using network and machine learning techniques uncovers modular communities of plasmid‐related virulence associated with IncF replicons. Accessory markers that are not directly linked to toxin genes can effectively predict the virulence status with an AUC of 0.85, facilitating
Sydney Menzeko Gambushe   +1 more
wiley   +1 more source

Blockade of Stx1 function reduces GBM cell proliferation in vitro.

open access: yes, 2015
A. Expression of exocytic SNARE machinery in several established GBM cell lines determined by immunoblot. B. Quantification of BrdU-positive nuclei in GBM cells.
Alba Gonzàlez-Juncà (710429)   +9 more
core   +1 more source

Host Factor Induced Bacterial Extracellular Vesicles Promote Horizontal Gene Transfer in Vibrio cholerae

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
Antimicrobial stressors, that is, bile or mitomycin C, induce enlarged, nucleic acid‐rich bacterial extracellular vesicles in Vibrio cholerae that facilitate horizontal gene transfer in vitro and during intestinal colonisation. The findings provide a detailed comparison of control versus stress‐induced vesicles, identify bile as a host factor shaping ...
Dominik Fleischhacker   +6 more
wiley   +1 more source

A conserved role for Syntaxin-1 in pre- and post-commissural midline axonal guidance in fly, chick, and mouse.

open access: yesPLoS Genetics, 2018
Axonal growth and guidance rely on correct growth cone responses to guidance cues. Unlike the signaling cascades that link axonal growth to cytoskeletal dynamics, little is known about the crosstalk mechanisms between guidance and membrane dynamics and ...
Oriol Ros   +11 more
doaj   +1 more source

Pathogenicity and Antimicrobial‐Resistance Profiles of Escherichia coli Isolated From Faeces of Tibetan Pigs Reared Under Intensive Conditions

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Tibetan pig farms host diverse Escherichia coli strains that resist multiple antibiotics and carry important disease genes, such as astA. These traits jump easily between bacterial groups, marking intensive pig production as a key reservoir and signalling the need for integrated animal–human surveillance and more careful antibiotic use.
Runbo Luo   +7 more
wiley   +1 more source

Imported Retail Beef and Chicken Meat Products Serve as Reservoirs for Emerging Antibiotic‐Resistant Pathotypes of Escherichia coli in Pristine Areas Free From Agricultural Activity

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Retail meat–derived E. coli frequently harbored multidrug‑resistance phenotypes, diverse virulence determinants, and plasmid‑encoded resistance genes with high conjugative potential. Results indicate meat and poultry as underrecognized reservoirs facilitating dissemination of antimicrobial resistance and pathogenic lineages, with imported products ...
Saehah Yi   +7 more
wiley   +1 more source

Information on Shiga toxin genes (stx1), and (stx1+stx2)-detected Escherichia coli positive samples.

open access: yes
Information on Shiga toxin genes (stx1), and (stx1+stx2)-detected Escherichia coli positive samples.
Park Y. Chul (17972670)   +2 more
core   +1 more source

Detection of subtypes of Stx1 and Stx2 toxoids using the universal sandwich ELISA.

open access: yes, 2016
A mixture of mAbs including mAbs Stx1-2, Stx2-5, Stx2b-1, Stx2e-2, and Stx2f-1 was used for capture (1 μg/mL each) and a mixture of Stx1 and Stx2 pAbs was used for detection (100 ng/mL each), the goat anti-rabbit IgG-HRP was used as a secondary antibody (
Xiaohua He (361530)   +4 more
core   +1 more source

Nitric oxide‐enhanced Shiga toxin production was regulated by Fur and RecA in enterohemorrhagic Escherichia coli O157

open access: yesMicrobiologyOpen, 2017
Enterohemorrhagic Escherichia coli (EHEC) produces Shiga toxin 1 (Stx1) and Shiga toxin 2 (Stx2). Nitric oxide (NO), which acts as an antimicrobial defense molecule, was found to enhance the production of Stx1 and Stx2 in EHEC under anaerobic conditions.
Kimitoshi Ichimura   +7 more
doaj   +1 more source

Isolation of Escherichia coli O157:H7 from Intact Colon Fecal Samples of Swine

open access: yesEmerging Infectious Diseases, 2003
Escherichia coli O157:H7 was recovered from colon fecal samples of pigs. Polymerase chain reaction confirmed two genotypes: isolates harboring the eaeA, stx1, and stx2 genes and isolates harboring the eaeA, stx1, and hly933 genes.
Ingrid Feder   +8 more
doaj   +1 more source

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