Results 61 to 70 of about 1,230,030 (294)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Light Logics and the Call-by-Value Lambda Calculus [PDF]
Logical Methods in Computer Science, 2008 The so-called light logics have been introduced as logical systems enjoying quite remarkable normalization properties. Designing a type assignment system for pure lambda calculus from these logics, however, is problematic.
Paolo Coppola +2 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
A Style-Shifting Analysis of Rumpletiltskin Speech In ‘Once Upon A Time’ Drama Series [PDF]
, 2021 This research aimed to identify and describe the style-shifting used by Rumpletiltskin in the drama series and the frequency he used in the drama. Benefit of this research is to give deeper knowledge for students or theater members in making a theater ...
Murni, Mustika
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Comments on "phase-shifting for nonseparable 2-D haar wavelets" [PDF]
, 2009 In their recent paper, Alnasser and Foroosh derive a wavelet-domain (in-band) method for phase-shifting of 2-D "nonseparable" Haar transform coefficients. Their approach is parametrical to the (a priori known) image translation.
Andreopoulos, Y
core
Profit Shifting opportunities, Multinationals, and the determinants of FDI [PDF]
, 2002 The theory of tax competition suggests that different tools might be used to attract physical capital and taxable profits. While it is assumed that FDI in real activity is deterred by high effective taxes, investment undertaken for purpose of profit ...
Stöwhase, Sven
core +1 more source
The Young and the Old: (t) Release in Elderspeak
Lifespans and Styles, 2017 Elderspeak refers to a speech style used when talking to the elderly. The aim of this study was to find out whether a higher rate of standard phonetic variants of phonemes is a feature of elderspeak.
James Michaelov
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source