Results 121 to 130 of about 3,745,344 (335)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Winter Wren by Theresa Kishkan [PDF]
, 2017 Review of Theresa Kishkan\u27s Winter ...
Hansen, Vivian M
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
LanguagesIn this article, I underscore the value of nuanced, speaker-focused approaches to dialect contact, which both complement and extend community-based perspectives. I pursue this goal through two main strategies.
Víctor Fernández-Mallat
doaj +1 more source
What has Translation Theory got to learn from Contemporary Practice? [PDF]
, 2004 There has long been a traditional animosity between practising translators and the theoreticians residing in the ‘Ivory Tower’ of the University. In the past, this was due to the judgmental attitude that theory would assume in relation to the translation
Bennett, Karen
core
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Playing Bebop: Culture and Bebop’s Reciprocal Influence
, 2016 Following the sweet, pleasant Swing era style music of the 1930’s, Bebop emerged within the United States as an aggressive, percussive, musician-focused style in the 1940’s. However, Bebop’s creation was not spontaneous.
DeBoy, Audra M.
core
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Embedded librarianship and problem-based learning in undergraduate mathematics courses [PDF]
, 2015 A pedagogical approach of problem-based learning with embedded librarianship in several undergraduate mathematics courses is implemented in this educational research.
Agee, J. +2 more
core +2 more sources