Results 101 to 110 of about 5,826,395 (224)

On expectation propagation for generalised, linear and mixed models

open access: yes, 2018
© 2018 Australian Statistical Publishing Association Inc. Published by John Wiley & Sons Australia Pty Ltd. Expectation propagation is a general approach to deterministic approximate Bayesian inference for graphical models, although its literature is ...
Andy S.I. Kim   +3 more
core   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Expectation-maximization approaches to independent component analysis

open access: yes, 2004
Expectation-Maximization (EM) algorithms for independent component analysis are presented in this paper. For super-Gaussian sources, a variational method is employed to develop an EM algorithm in closed form for learning the mixing matrix and inferring ...
Zhong, MJ, Tang, HW, Tang, YY
core  

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Note on the complete moment convergence for moving average process of a class of random variables under sub-linear expectations [PDF]

open access: yes
In this paper, the complete moment convergence for the partial sums of moving average processes $\{X_n=\sum_{i=-\infty}^{\infty}a_iY_{i+n},n\ge 1\}$ is proved under some proper conditions, where $\{Y_i ...
Xu, Mingzhou
core  

Customer satisfaction function Cm,n.

open access: yes, 2014
(a) and (b) depict the distributions of customer satisfaction as recorded at the fixed expectation Hexp = 0.7 and Hexp = 0.9, where the parameter δ is varied from 2 to 6 in increment of 2.
Kai-Le Zhou (589975)   +4 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Effect Comparison in linear mixed models for eGFRMDRD and eGFRCKD-EPI.

open access: yes, 2015
Effect Comparison in linear mixed models for eGFRMDRD and eGFRCKD-EPI.
Max Plischke (544192)   +6 more
core   +1 more source

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