Results 201 to 210 of about 193,366 (266)

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood   +7 more
wiley   +1 more source

Ischemic heart disease burden and healthcare system readiness across sub-Saharan Africa. [PDF]

open access: yesNat Cardiovasc Res
Khurana MP   +13 more
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Clinicopathological Analysis of 358 Ovarian Tumors from a Sub-Saharan African Country. [PDF]

open access: yesInt J Womens Health
Efared B   +6 more
europepmc   +1 more source

Management strategies for healthcare worker burnout in Sub-Saharan Africa: an integrative review. [PDF]

open access: yesFront Public Health
Khangamwa-Singano F   +4 more
europepmc   +1 more source

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