Subacute Combined Degeneration Caused by Nitrous Oxide Intoxication: A Report of Two Cases [PDF]
We report two cases of subacute combined degeneration (SCD) caused by nitrous oxide (N2O) gas intoxication, which is rarely reported in Korea. Two patients recreationally inhaled N2O gas daily for several months. They presented with paresthesia of limbs,
Cheol Choi +4 more
doaj +1 more source
Nitrous Oxide as an Emerging Cause of Subacute Combined Degeneration and Polyneuropathy: A Two-Case Report. [PDF]
Recreational use of nitrous oxide (N2O), commonly known as laughing gas, has increased in the last few years, bringing an increase in the number of reported cases of toxicity due to this gas. Subacute combined degeneration (SCD) of the spinal cord is the
Pino S, Vega E, Fragoso M, Salazar G.
europepmc +2 more sources
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Recreational Nitrous Oxide Causing Deep Vein Thrombosis and Subacute Combined Degeneration: Whip It Real Good. [PDF]
Nitrous oxide (N2O) has been thought to be a harmless recreational substance by public perception, but it has been linked to subacute combined degeneration (SACD) due to induction of a functional vitamin B12 deficiency via oxidation and inactivation of ...
Lander ME, Lander SJ, Park J, Chae C.
europepmc +2 more sources
A Rare Case of Folate Deficiency-Induced Subacute Combined Degeneration of the Spinal Cord: A Case Report. [PDF]
Folate deficiency is a rare cause of subacute combined degeneration (SCD). SCD is characterized by demyelination of the dorsal and lateral columns of the cervical and thoracic spine most commonly caused by vitamin B12 deficiency. Folate deficiency, which
Guntupalli L, Lurie A, Stoll V, Lugo LD.
europepmc +2 more sources
Global Burden Related to Nitrous Oxide Exposure in Medical and Recreational Settings: A Systematic Review and Individual Patient Data Meta-Analysis. [PDF]
The risk of adverse effects of nitrous oxide (N2O) exposure is insufficiently recognized despite its widespread use. These effects are mainly reported through case reports. We conducted an individual patient data meta-analysis to assess the prevalence of
Filhine-Tresarrieu, Pierre +10 more
core +3 more sources
Background Nitrous oxide (N2O), a long-standing anesthetic, is also neurotoxic by interfering with the bioavailability of vitamin B12 if abused. A few case studies have reported the neurological and psychiatric complications of N2O.
Jun Liang Yuan +3 more
doaj +1 more source
Falling From Laughing: Laughing Gas-Induced Subacute Combined Degeneration From Nitrous Oxide. [PDF]
Laughing gas is becoming increasingly popular as a recreational drug of choice, particularly among young adults. Nitrous oxide, the toxic component of laughing gas, can cause neuronal injury when used in high doses.
Rao AK +4 more
europepmc +2 more sources
Pitfalls in the diagnostic evaluation of subacute combined degeneration [PDF]
We report a case of a 43-year-old man presenting with a 2-week history of painless ascending sensory disturbances, suspected to be suffering from acute inflammatory polyneuropathy.
Linnebank, M +3 more
core +1 more source
Correlation Between Nitrous Oxide and Functional Vitamin B12 Deficiency Resulting in Subacute Combined Degeneration of the Spinal Cord: A Case Report. [PDF]
Nitrous oxide (N2O) is generally used in the medical and food industries. However, it is sometimes illegally misused by young adults as a recreational drug.
Kyaw KY, Lwin MT, Lwin ZT.
europepmc +2 more sources

