Results 121 to 130 of about 1,315,337 (287)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Minorities, violences, rights: notes for thinking the respect in gender and sexuality dissent.
Travessias, 2017 Inspired by the discussions I have conducted in my undergraduate classes and by two essays I have published on high impact social media, this text is intended to discuss the legitimacy of violence committed by gender and sexuality minorities as an often ...
Carlos Henrique Lucas Lima
doaj
Khaled Hosseini's women as modern archetypes: A study of obedient, resistant and empowered Afghan women. [PDF]
Front Sociol, 2022 Imran M, Ismail SM.
europepmc +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
SocietiesLearning the host language is a crucial factor in the settlement of migrants and refugees in a new country. It offers opportunities, but can also generate exclusion, marginalization, and isolation, hindering the possibilities of participation and the ...
Maria Luís Queirós +2 more
doaj +1 more source
Popular culture, subaltern culture, and class culture
Anuac, 2019 Nota critica di Fabio Dei, Antonio Fanelli, a cura di, La demologia come “scienza normale”? Ripensare Cultura egemonica e culture subalterne, Lares, 81, 2-3, Maggio-Dicembre 2015, pp. 239; Fabio Dei, Cultura popolare in Italia: Da Gramsci all’Unesco, Bologna, il Mulino, 2018, pp. 274.
openaire +2 more sources
A Subaltern Study of Maria Campbell's Half-Breed
, 2018 The terms Subaltern and Subaltern Studies entered Post Colonial studies through the works of a group of South Asian scholars who were interested in the Post Colonial societies and it was started in the University of Sussex.
K.Swathi
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Understanding urban processes in Flint, Michigan:Approaching 'subaltern urbanism' inductively
, 2013 Ananya Roy introduces the concept 'subaltern urbanism' in her 2011 article 'Slumdog Cities: Rethinking Subaltern Urbanism'. She challenges researchers to move beyond existing epistemological and methodological limits, and offers four concepts which ...
Schindler, Seth; id_orcid +1 more
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source