Results 131 to 140 of about 1,315,337 (287)
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Negotiating Caste and Class: Subaltern Voices in Bama's Short Stories
This paper examines the representation of subaltern voices in Bama's short stories through the interconnected lenses of caste and class. Drawing upon Gayatri Chakravorty Spivak's concept of the subaltern and the framework of Subaltern Studies, the paper analyses “The Grazing Fields”, “This Man”, “The Yellow Butterfly”, and “Worldly Wisdom”.
openaire +2 more sources
Subaltern Urbanisation Revisited
Réédition de: "Subaltern Urbanization Revisited", P Mukhopadhyay, MH Zerah, E Denis - India International Centre Quarterly, 2017International audienceWhen we used the phrase ‘subaltern urbanisation’ (Denis, et al., 2012), we were quite up front about it ...
Denis, Eric +2 more
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
At the fabric of history: Peru's political struggle under (and against) the pandemic. [PDF]
Mitrovic M.
europepmc +1 more source
Subaltern Classes, Class Struggles and Hegemony : a Gramscian Approach
O artigo procura resgatar, no pensamento de Antonio Gramsci, a concepção de classes subalternas e a sua relação com outras categorias, especialmente, o Estado, a sociedade civil e a hegemonia, como suportes da luta de classes na realidade contemporânea. Aborda, ainda, as relações entre classes subalternas, senso comum e ideologia, bem como as formas de
openaire +1 more source
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Colonial Biopolitics and the Great Bengal Famine of 1943. [PDF]
Mallik S.
europepmc +1 more source

