Results 81 to 90 of about 1,315,337 (287)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A ASSISTÊNCIA SOCIAL NO PROCESSO DE RESTAURAÇÃO DA DOMINAÇÃO BURGUESA NO BRASIL
Revista de Políticas Públicas, 2014 This paper examines the mediations (institutional, political-ideological and socioeconomic) activated through the field of social assistance that contributes to the consolidation of bourgeois hegemony in Brazil.
Adilson Aquino Silveira Júnior +1 more
doaj
Manuela, de Eugenio Díaz Castro, o la novela sobre el impasse de fundación nacional
Estudios de Literatura Colombiana, 2013 Resumen: Éste artículo es una aproximación aManuela, la novela de Eugenio Díaz Castro, desde la perspectiva de los Estudios Subalternos. Argumenta que el novelista ilustró "desde abajo" los principales obstáculos del proyecto de consolidación nacional ...
Sergio Escobar
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Subaltern Vision : A Study in Postcolonial Indian English Text
, 2012 Ever since the Gramscian notion of the subaltern became the lynch-pin of the counter-hegemonic project developed by the Subaltern Studies group in the early 1980s, attempts to give voice to India's unrepresented or under-represented classes have played a
Jana, Ujjwal, +2 more
core
Subaltern Studies: considerações teórico-metodológicas e crítica ao viés pós-estruturalista
This article presents a discussion on the meaning of the Gramscian concept of subaltern classes and groups and its use by Indian Subaltern Studies researchers Ranajit Guha and Gayatri C. Spivak.
Leandro Galastri
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Subaltern urbanisation revisited
, 2017 Réédition de: "Subaltern Urbanization Revisited", P Mukhopadhyay, MH Zerah, E Denis - India International Centre Quarterly, 2017International audienceWhen we used the phrase ‘subaltern urbanisation’ (Denis, et al., 2012), we were quite up front about it ...
Denis, Eric +7 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source