Results 181 to 190 of about 715,613 (310)

Lcn2 Promotes Ferroptosis in Intracerebral Hemorrhage by Targeting Keap1 Tyr572 and Restricting Nrf2 Activation

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This study reveals that Lcn2 regulates ferroptosis after ICH via the Keap1/Nrf2 axis. Neuronal Lcn2 deletion reduces lipid peroxidation, restores mitochondrial function, and improves ferroptosis. Keap1 Tyr572Ala mutant acts as a molecular switch whose effects invert with Lcn2 status.
Ya‐nan Dou   +14 more
wiley   +1 more source

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu   +6 more
wiley   +1 more source

Hypothalamic adipsia presenting as persistent hypernatremia after aneurysmal subarachnoid hemorrhage. [PDF]

open access: yesJCEM Case Rep
Rodríguez Jiménez B   +5 more
europepmc   +1 more source

Novel Therapeutic Insights Into Alzheimer's Disease: Glymphatic System and Meningeal Lymphatic Vessels

open access: yesAging Cell, Volume 25, Issue 9, September 2026.
The identification of the glymphatic system (GS) and meningeal lymphatic vessels (mLVs) challenges the century‐old “immune‐privileged” dogma of the central nervous system (CNS), establishing a critical mechanistic link between impaired waste clearance (Aβ/tau) and the pathogenesis of Alzheimer's disease (AD).
Bingbing Song   +10 more
wiley   +1 more source

Stretching the Limits: A Rare Case Report of Perimesencephalic Subarachnoid Hemorrhage During Yoga. [PDF]

open access: yesClin Pract Cases Emerg Med
Vierra A   +5 more
europepmc   +1 more source

Induced Hypertension for Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage: A Randomized Clinical Trial

open access: yesStroke, 2018
C. Gathier   +24 more
semanticscholar   +1 more source

Long‐term neurological and psychiatric outcomes after paediatric arterial ischaemic stroke and cerebral sinovenous thrombosis

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 9, Page 1237-1245, September 2026.
Arterial ischemic stroke (AIS) or cerebral sinovenous thrombosis (CSVT) is a rare but serious event in children and adolescents. A descriptive long‐term (median 16 years) follow‐up study of patients revealed an increased risk of neurological and psychiatric diagnoses after AIS or CSVT, highlighting significant morbidity compared with the general ...
Jeanette Soenderlyng Springer   +4 more
wiley   +1 more source

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