Results 191 to 200 of about 715,613 (310)

The Therapeutic Potential of Purmorphamine Across Disease Models

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.
ABSTRACT Purmorphamine (PUR) is a trisubstituted purine compound that selectively activates Smoothened receptor, thereby initiating Sonic Hedgehog (Shh) signalling—a pathway critical for embryonic patterning, neuronal specification and tissue regeneration across multiple organ systems. Dysregulation of Shh signalling has been implicated in degenerative
Ashis Dhar   +4 more
wiley   +1 more source

Factors Associated With Accelerated Fracture Healing in Patients With Traumatic Brain Injury and Extremity Comminuted Fractures: A Retrospective Case–Control Study

open access: yesOrthopaedic Surgery, Volume 18, Issue 9, Page 1880-1891, September 2026.
In patients with traumatic brain injury and comminuted fractures, accelerated healing is independently predicted by younger age and greater TBI severity (lower GCS score). These factors may inform clinical decision‐making and provide insight into neurohumoral regulation of bone regeneration.
Xueqian Li   +6 more
wiley   +1 more source

Intra-arterial nimodipine and outcomes in delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. [PDF]

open access: yesBrain Spine
Pesonen EK   +5 more
europepmc   +1 more source

Comment on Pituitary Tumour Apoplexy as Cause of Death of Simonetta Vespucci

open access: yes
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Alexis Demas
wiley   +1 more source

Topliss‐Guided Optimization of Acetanilide‐Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency‐Enhancing Motif

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
Can an amide analog retain the high potency of the classic urea motif in soluble epoxide hydrolase inhibitors? Through a single unconventional switch, the introduction of the underexplored pentafluorosulfanyl group into an amide analog of TPPU, the authors restored high inhibitory potency.
Alba López‐Ruiz   +17 more
wiley   +1 more source

Changes in serum sodium during an external ventricular drain weaning in patients with subarachnoid hemorrhage. [PDF]

open access: yesFront Neurol
Horton P   +7 more
europepmc   +1 more source

An introduction to the pathophysiology of aneurysmal subarachnoid hemorrhage

open access: yesNeurosurgical review, 2018
J. V. van Lieshout   +9 more
semanticscholar   +1 more source

Cilostazol and Functional Outcomes in Poor-Grade Aneurysmal Subarachnoid Hemorrhage: A Multicenter Retrospective Analysis. [PDF]

open access: yesJ Clin Med
Kikuchi J   +16 more
europepmc   +1 more source

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