Results 11 to 20 of about 715,613 (310)

Early Brain Injury After Subarachnoid Hemorrhage: Incidence and Mechanisms

open access: yesStroke, 2023
Aneurysmal subarachnoid hemorrhage is a devastating condition causing significant morbidity and mortality. While outcomes from subarachnoid hemorrhage have improved in recent years, there continues to be significant interest in identifying therapeutic ...
Rajat Dhar   +2 more
exaly   +2 more sources

Microglia activation, classification and microglia-mediated neuroinflammatory modulators in subarachnoid hemorrhage

open access: yesNeural Regeneration Research, 2022
Subarachnoid hemorrhage is a devastating disease with significant mortality and morbidity, despite advances in treating cerebral aneurysms. There has been recent progress in the intensive care management and monitoring of patients with subarachnoid ...
Junfan Chen   +5 more
doaj   +2 more sources

The pivotal role of microglia in injury and the prognosis of subarachnoid hemorrhage

open access: yesNeural Regeneration Research
Subarachnoid hemorrhage leads to a series of pathological changes, including vascular spasm, cellular apoptosis, blood–brain barrier damage, cerebral edema, and white matter injury. Microglia, which are the key immune cells in the central nervous system,
Wenjing Ning   +3 more
doaj   +2 more sources

An early neuroprotective effect of atorvastatin against subarachnoid hemorrhage

open access: yesNeural Regeneration Research, 2020
Atorvastatin has been shown to reduce early brain edema and neuronal death after subarachnoid hemorrhage, but its mechanism is not clear. In this study, rat models of subarachnoid hemorrhage were established by autologous blood injection in the cisterna ...
Jun-Hui Chen   +7 more
doaj   +2 more sources

Potential therapeutic molecular targets for blood-brain barrier disruption after subarachnoid hemorrhage

open access: yesNeural Regeneration Research, 2019
Aneurysmal subarachnoid hemorrhage remains serious hemorrhagic stroke with high morbidities and mortalities. Aneurysm rupture causes arterial bleeding-induced mechanical brain tissue injuries and elevated intracranial pressure, followed by global ...
Hideki Kanamaru, Hidenori Suzuki
doaj   +2 more sources

Experimental and Clinical Treatment of Subarachnoid Hemorrhage after the Rupture of Saccular Intracranial Aneurysms [PDF]

open access: yesBrain Sciences, 2020
The Special Issue “Experimental and Clinical Treatment of Subarachnoid Hemorrhage after the Rupture of Saccular Intracranial Aneurysms” provides an excellent insight into the many facets of aneurysmal subarachnoid hemorrhage [...]
Serge Marbacher, John H. Zhang
doaj   +2 more sources

Lumbar drainage following aneurysmal subarachnoid haemorrhage and the role of cytokine and adhesion molecules in the pathogenesis of delayed ischaemic neurological deficit [PDF]

open access: yes, 2011
Introduction Delayed ischaemic neurological deficit (DIND) following aneurysmal subarachnoid haemorrhage (aSAH) is a significant cause of morbidity and mortality.
Al-Tamimi, Yahia
core   +6 more sources

2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage: A Guideline From the American Heart Association/American Stroke Association.

open access: yesStroke, 2023
AIM The "2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage" replaces the 2012 "Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage." The 2023 guideline is intended to provide patient-centric ...
B. Hoh   +20 more
semanticscholar   +1 more source

Investigating Recovery After Subarachnoid Hemorrhage With the Imaging, Cognition and Outcome of Neuropsychological Functioning After Subarachnoid Hemorrhage (ICONS) Study: Protocol for a Longitudinal, Prospective Cohort Study

open access: yesJMIR Research Protocols, 2022
BackgroundA subarachnoid hemorrhage is a hemorrhage in the subarachnoid space that is often caused by the rupture of an aneurysm. Patients who survive a subarachnoid hemorrhage have a high risk of complications and a negative long-
Sara Khosdelazad   +8 more
doaj   +1 more source

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