Results 21 to 30 of about 62,746 (218)

The pivotal role of microglia in injury and the prognosis of subarachnoid hemorrhage

Neural Regeneration Research
Subarachnoid hemorrhage leads to a series of pathological changes, including vascular spasm, cellular apoptosis, blood–brain barrier damage, cerebral edema, and white matter injury. Microglia, which are the key immune cells in the central nervous system,
Wenjing Ning, Shi Lv, Qian Wang, Yuzhen Xu   +3 more
doaj   +1 more source

Potential therapeutic molecular targets for blood-brain barrier disruption after subarachnoid hemorrhage

Neural Regeneration Research, 2019
Aneurysmal subarachnoid hemorrhage remains serious hemorrhagic stroke with high morbidities and mortalities. Aneurysm rupture causes arterial bleeding-induced mechanical brain tissue injuries and elevated intracranial pressure, followed by global ...
Hideki Kanamaru, Hidenori Suzuki
doaj   +1 more source

Phosphodiesterase 4 regulates pyroptosis in subarachnoid hemorrhage

Neural Regeneration Research
Phosphodiesterase 4 is a key enzyme involved in the regulation of cell signal transduction, but its role in subarachnoid hemorrhage remains unclear. Neuronal pyroptosis has been reported to be involved in early brain injury after subarachnoid hemorrhage.
Jiahe Tan, Yinrui Ma, Rui Song, Hongjiang Ye, Jun Su, Zhaohui He   +5 more
doaj   +1 more source

Dynamic expression of nerve growth factor and its receptor TrkA after subarachnoid hemorrhage in rat brain

Neural Regeneration Research, 2016
Delayed ischemic neurologic deficit after subarachnoid hemorrhage results from loss of neural cells. Nerve growth factor and its receptor TrkA may promote regeneration of neural cells, but their expression after subarachnoid hemorrhage remains unclear ...
Jin-ning Song, Zun-wei Liu, Long Sui, Bin-fei Zhang, Yong-lin Zhao, Xu-dong Ma, Hua Gu   +6 more
doaj   +1 more source

A novel intravital method to evaluate cerebral vasospasm in rat models of subarachnoid hemorrhage: a study with synchrotron radiation angiography. [PDF]

PLoS ONE, 2012
Precise in vivo evaluation of cerebral vasospasm caused by subarachnoid hemorrhage has remained a critical but unsolved issue in experimental small animal models. In this study, we used synchrotron radiation angiography to study the vasospasm of anterior
Jun Cai, Yuhao Sun, Falei Yuan, Lujia Chen, Chuan He, Yuhai Bao, Zuoquan Chen, Meiqing Lou, Weiliang Xia, Guo-Yuan Yang, Feng Ling   +10 more
doaj   +1 more source

Unmasking a subarachnoid hemorrhage [PDF]

Neurology, 2013
A 53-year-old patient presented with acute headache. CT and intra/extracranial CT angiography were normal. A traumatic lumbar puncture showed 8,500 erythrocytes/mm3 and 24 leukocytes/mm3. MRI showed extensive sulcal fluid-attenuated inversion recovery (FLAIR) hyperintensities suggesting subarachnoid hemorrhage (figure).
Giovanni, Castelnovo, Dimitri, Renard
openaire   +2 more sources

A Case of Sudden Death: Subarachnoid Hemorrhage, Pheochromocytoma, Berry Aneurysm

Case Reports in Pathology, 2019
Subarachnoid hemorrhage is a medical emergency. Berry aneurysm rupture is the second most common cause following trauma. Diagnosis is often challenging. Neurogenic heart syndrome often complicates subarachnoid hemorrhage.
Ana B. Arevalo, Jacxelyn Moran, Stephen Zink, Binny Khandakar   +3 more
doaj   +1 more source

Massive traumatic subarachnoid hemorrhage mimicking aneurysmal subarachnoid hemorrhage

Trauma Case Reports, 2023
Introduction: Massive traumatic subarachnoid hemorrhage (tSAH) is a rare but potentially life-threatening condition that can mimic the clinical presentation of aneurysmal subarachnoid hemorrhage (aSAH).
Amr Rachid El Mohamad, Muhammad Mohsin Khan, Rand Y. Omari, Gustav Strandvik   +3 more
doaj   +1 more source

Neuroprotection in Subarachnoid Hemorrhage [PDF]

Stroke, 2010
Despite advances in aneurysm ablation and the initial management of patients presenting with aneurysmal subarachnoid hemorrhage, delayed cerebral ischemia remains a significant source of morbidity. Traditionally, delayed cerebral ischemia was thought to be a result of vasospasm of the proximal intracranial vessels, and clinical trials have relied ...
Daniel T, Laskowitz, Brad J, Kolls
openaire   +2 more sources

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source