Results 91 to 100 of about 428,606 (255)

Molecular profile of adult primary leptomeningeal gliomatosis aligns with glioblastoma, IDH‐wildtype

open access: yesBrain Pathology, EarlyView.
The molecular profile of adult primary leptomeningeal gliomatosis closely aligned with that of adult‐type glioblastoma, IDH‐wildtype, CNS WHO grade 4. Abstract Adult primary leptomeningeal gliomatosis (PLG) is a rare, rapidly progressive and fatal disease characterized by prominent leptomeningeal infiltration by a glial tumor without an identifiable ...
Yi Zhu   +14 more
wiley   +1 more source

Differential impact of acute fine particulate matter exposure on risk of stroke by stroke subtype, age, sex, and race: a case-crossover study [PDF]

open access: yesarXiv, 2019
Objective: Association between acute ambient fine particulate matter (PM2.5, aerodynamic diameter less than 2.5 and cardiovascular events are well documented. However, it remains unclear whether acute exposure to PM2.5 acts as a trigger for hemorrhagic (intracerebral or subarachnoid hemorrhage) or non-hemorrhagic (infarct or transient ischemic attack ...
arxiv  

Subarachnoid Space: New Tricks by an Old Dog

open access: yesPLoS ONE, 2012
The purpose of the study was to: (1) evaluate the subarachnoid space (SAS) width and pial artery pulsation in both hemispheres, and (2) directly compare magnetic resonance imaging (MRI) to near-infrared transillumination/backscattering sounding (NIR-T/BSS) measurements of SAS width changes in healthy volunteers.The study was performed on three separate
Pawel J. Winklewski   +3 more
openaire   +5 more sources

Potentiating microglial efferocytosis by MFG‐E8 improves survival and neurological outcome after successful cardiopulmonary resuscitation in mice

open access: yesBrain Pathology, EarlyView.
Schematic representation of the effects of rmMFG‐E8 on post‐CA/CPR brain injury. Ischemic/reperfusion injury caused by CA/RCA results in elevated apoptotic cell death in various cells and decreased apoptotic cell clearance by phagocytes, such as microglia.
Kunxue Zhang   +9 more
wiley   +1 more source

Oscillating flow around a circular cylindrical post confined between two parallel plates [PDF]

open access: yesarXiv
This work is motivated by the interest in determining the effect of the micro-anatomy of the spinal subarachnoid space on the cerebrospinal fluid flow and on the associated transport of solutes. To that aim, we focus on a canonical model problem in which a circular post of radius $a$, confined between two parallel plates separated by a distance $2h ...
arxiv  

Opportunities to Modulate Tumor Ecosystem Toward Successful Glioblastoma Immunotherapy

open access: yesCancer Science, EarlyView.
There remain outstanding gaps between the negative results from clinical trials and the actual potential of the immune system for glioblastoma. To bridge this crucial gap, we collaborated with Dr. Mariko Takahashi, an expert in immunobiology and drug development, and Dr. James J.
Mariko Takahashi   +5 more
wiley   +1 more source

Pseudo-subarachnoid hemorrhage and gadolinium encephalopathy following lumbar epidural steroid injection

open access: yesRadiology Case Reports, 2020
Patients with imaging findings concerning for subarachnoid hemorrhage, however, with no evidence of hemorrhage following autopsy or cerebrospinal fluid testing are diagnosed with having pseudo-subarachnoid hemorrhage.
Andrew Platt, MD   +4 more
doaj  

Causal Graph Aided Causal Discovery in an Observational Aneurysmal Subarachnoid Hemorrhage Study [PDF]

open access: yesarXiv
Causal inference methods for observational data are increasingly recognized as a valuable complement to randomized clinical trials (RCTs). They can, under strong assumptions, emulate RCTs or help refine their focus. Our approach to causal inference uses causal directed acyclic graphs (DAGs). We are motivated by a concern that many observational studies
arxiv  

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