Results 141 to 150 of about 4,838,802 (318)

SUBA4 : the interactive data analysis centre for Arabidopsis subcellular protein locations [PDF]

open access: yes, 2016
The SUBcellular location database for Arabidopsis proteins (SUBA4, http://suba.live) is a comprehensive collection of manually curated published data sets of large-scale subcellular proteomics, fluorescent protein visualization, protein-protein ...
Millar, A. Harvey   +4 more
core   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

open access: yesAdvanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang   +5 more
wiley   +1 more source

Protein subcellular localization prediction tools

open access: yesComputational and Structural Biotechnology Journal
Protein subcellular localization prediction is of great significance in bioinformatics and biological research. Most of the proteins do not have experimentally determined localization information, computational prediction methods and tools have been ...
Maryam Gillani, G. Pollastri
semanticscholar   +1 more source

Subcellular location and expression of Halo-zDHHC20 and Halo-zDHHC5 in Flp-In 293 T-REx cells.

open access: yes
A–Subcellular location of Halo-zDHHC5 visualised by staining cells with TAMRA-chloroalkane either without (uninduced) or with (induced) gene induction using tetracycline.
Elaine Brown (225503)   +11 more
core   +1 more source

Overview of the A) subcellular location, B) molecular size distribution and C) molecular and cellular functions of the 135 proteins that showed significant variation between irradiated and sham skin tissues.

open access: yes, 2014
Others: subcellular location known, but not being included in the main categories; Unknown: subcellular location unknown. Protein may have more than one function.
Melissa Matzke (538621)   +9 more
core   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang   +9 more
wiley   +1 more source

Many Local Pattern Texture Features: Which Is Better for Image-Based Multilabel Human Protein Subcellular Localization Classification?

open access: yesThe Scientific World Journal, 2014
Human protein subcellular location prediction can provide critical knowledge for understanding a protein’s function. Since significant progress has been made on digital microscopy, automated image-based protein subcellular location classification is ...
Fan Yang, Ying-Ying Xu, Hong-Bin Shen
doaj   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

open access: yesAdvanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao   +7 more
wiley   +1 more source

Peroxidase proximity selection to identify aptamers targeting a subcellular location. [PDF]

open access: yesPNAS Nexus, 2023
Wilbanks B   +4 more
europepmc   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

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