Results 121 to 130 of about 4,838,802 (318)

Subcellular Location and Unique Secretion of the Hemolysin of Serratia marcescens

Journal of Biological Chemistry, 1989
It is shown that Serratia marcescens exports a hemolysin to the cell surface and secretes it to the extracellular space. Escherichia coli containing the cloned hemolysin genes shlA and shlB exported and secreted the S. marcescens hemolysin. A nonhemolytic secretion-incompetent precursor of the hemolysin, designated ShlA*, was synthesized in a shlB ...
Schiebel, E., Schwarz, H., Braun, V. ; https://orcid.org/0000-0003-0093-8595   +2 more
openaire   +3 more sources

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

iLoc-Euk: a multi-label classifier for predicting the subcellular localization of singleplex and multiplex eukaryotic proteins.

PLoS ONE, 2011
Predicting protein subcellular localization is an important and difficult problem, particularly when query proteins may have the multiplex character, i.e., simultaneously exist at, or move between, two or more different subcellular location sites.
Kuo-Chen Chou, Zhi-Cheng Wu, Xuan Xiao
doaj   +1 more source

Magnetoactive Hydrogels to Probe Curvature‐Directed Endothelial Cell Mechanosensing

Advanced Healthcare Materials, EarlyView.
This work establishes a platform to investigate local curvature as a regulator of endothelial mechanosensing independent of shear stress. Magnetoactive hydrogels enable on‐demand curvature of endothelial monolayers to reproduce tortuosity quantified by clinically established metrics.
Avinava Roy, Grace K. Hinds, Joshua Yu‐Chung Liu, Ziqian Yang, Rishab Yanala, Arina E. Velieva, Claudia Loebel   +6 more
wiley   +1 more source

Rice DB: an Oryza Information Portal linking annotation, subcellular location, function, expression, regulation, and evolutionary information for rice and Arabidopsis

The Plant Journal, 2013
Omics research in Oryza sativa (rice) relies on the use of multiple databases to obtain different types of information to define gene function. We present Rice DB, an Oryza information portal that is a functional genomics database, linking gene loci to ...
Reena Narsai, J. Devenish, I. Castleden, Kabir Narsai, Lin Xu, Hui-Xia Shou, J. Whelan   +6 more
semanticscholar   +1 more source

Advances in Bio‐Integrated Edge Computing Systems for Smart and Connected Health

Advanced Materials, EarlyView.
This review explores advances in bio‐integrated edge computing for healthcare, focusing on co‐designing computing, sensing, and energy strategies to overcome integration and power challenges for optimized, decentralized operation. ABSTRACT Recent advances in bio‐integrated healthcare technologies have enabled continuous, high‐resolution monitoring and ...
Gyuwon Kim, Seungwon Yoo, Tae Woog Kang, Yunuo Huang, Woon‐Hong Yeo   +4 more
wiley   +1 more source

Cellular and Molecular Mechanisms Underlying Synaptic Subcellular Specificity

Brain Sciences
Chemical synapses are essential for neuronal information storage and relay. The synaptic signal received or sent from spatially distinct subcellular compartments often generates different outcomes due to the distance or physical property difference ...
Mengqing Wang, Jiale Fan, Zhiyong Shao
doaj   +1 more source

Prediction of protein subcellular localization using support vector machine with the choice of proper kernel

BioTechnologia, 2017
The prediction of subcellular locations of proteins can provide useful hints for revealing their functions as well as for understanding the mechanisms of some diseases and, finally, for developing novel drugs.
Al Mehedi Hasan, Shamim Ahmad, Khademul Islam Molla   +2 more
doaj   +1 more source

Predicting subcellular locations of eukaryotic proteins using Bayesian and k-nearest neighbor classifiers [PDF]

, 2010
[[abstract]]Biologically, the function of a protein is highly related to its subcellular location. It is of necessity to develop a reliable method for protein subcellular location prediction, especially when a large amount of proteins are to be analyzed.
Han C.W. Hsiao;S.H. Chen;P.C. Chang;Jeffrey J.P. Tsai, Han-Wen Hsiao;Shih-Hao Chen;Pei-Chun Chang;Jeffery J.P. Tsai   +1 more
core  

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source