Results 271 to 280 of about 4,838,802 (318)
Some of the next articles are maybe not open access.
Multitask Learning for Protein Subcellular Location Prediction
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2011Protein subcellular localization is concerned with predicting the location of a protein within a cell using computational methods. The location information can indicate key functionalities of proteins. Thus, accurate prediction of subcellular localizations of proteins can help the prediction of protein functions and genome annotations, as well as the ...
Qian Xu 0005 +3 more
openaire +4 more sources
Location Proteomics: Systematic Determination of Protein Subcellular Location
2009Proteomics seeks the systematic and comprehensive understanding of all aspects of proteins, and location proteomics is the relatively new subfield of proteomics concerned with the location of proteins within cells. This review provides a guide to the widening selection of methods for studying location proteomics and integrating the results into systems
Justin, Newberg +2 more
openaire +2 more sources
Prediction of Protein Structural Classes and Subcellular Locations
Current Protein and Peptide Science, 2000The structural class and subcellular location are the two important features of proteins that are closely related to their biological functions. With the rapid increase in new protein sequences entering into data banks, it is highly desirable to develop a fast and accurate method for predicting the attributes of these features for them.
Kuo-Chen Chou, K-C Chou
exaly +3 more sources
Location proteomics: a systems approach to subcellular location
Biochemical Society Transactions, 2005Systems Biology requires comprehensive systematic data on all aspects and levels of biological organization and function. In addition to information on the sequence, structure, activities and binding interactions of all biological macromolecules, the creation of accurate predictive models of cell behaviour will require detailed information on the ...
openaire +2 more sources
Recent progress in protein subcellular location prediction
Analytical Biochemistry, 20070003-2697/$ see front matter 2007 Elsevier Inc. All rights reserve doi:10.1016/j.ab.2007.07.006 * Corresponding author. E-mail address: kcchou@gordonlifescience.org (K.-C. Chou). With a typical size of 10 lm and a typical mass of 1 ng, the cell is deemed to be the most basic structural and functional unit of all living organisms and often is called a ‘‘
Kuo-Chen, Chou, Hong-Bin, Shen
openaire +2 more sources
Multilabel Learning for Protein Subcellular Location Prediction
IEEE Transactions on NanoBioscience, 2012Protein subcellular localization aims at predicting the location of a protein within a cell using computational methods. Knowledge of subcellular localization of proteins indicates protein functions and helps in identifying drug targets. Prediction of protein subcellular localization is an important but challenging problem, particularly when proteins ...
Guo-Zheng, Li +4 more
openaire +2 more sources
Importance of the subcellular location of protein deposits in neurodegenerative diseases.
Current Opinion in Neurobiology, 2018Alzheimer's disease, Parkinson's, Huntington's, amyotrophic lateral sclerosis (ALS) and prion disorders are devastating neurodegenerative diseases of increasing prevalence in aging populations.
A. Bertolotti
semanticscholar +1 more source
Using AdaBoost for the Prediction of Subcellular Location of Prokaryotic and Eukaryotic Proteins
Molecular Diversity, 2008 In this paper, AdaBoost algorithm, a popular and effective prediction method, is applied to predict the subcellular locations of Prokaryotic and Eukaryotic Proteins-a dataset derived from SWISSPROT 33.0.
Guo-zheng Li, Yudong Cai, Bing Niu
exaly +1 more source
The Akt isoforms are present at distinct subcellular locations
American Journal of Physiology-Cell Physiology, 2010Akt is involved in the regulation of diverse cellular functions such as cell proliferation, energy metabolism, and apoptosis. Although three Akt isoforms are known, the function of each isoform is poorly understood. To gain a better understanding of each Akt isoform, we examined the subcellular localization and expression of each isoform in ...
Stacey A, Santi, Hoyun, Lee
openaire +2 more sources
Automated interpretation of subcellular location patterns
2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (IEEE Cat No. 04EX821), 2005Fluorescence microscopy is widely used to analyze the distribution of proteins within cells. As currently practiced, the assignment of a protein to a particular organelle is done by visual inspection of images or comparison between the distribution of the unknown protein and markers with known location patterns.
openaire +2 more sources