Results 41 to 50 of about 4,838,802 (318)
A multi-label classifier for predicting the subcellular localization of gram-negative bacterial proteins with both single and multiple sites. [PDF]
PLoS ONE, 2011 Prediction of protein subcellular localization is a challenging problem, particularly when the system concerned contains both singleplex and multiplex proteins. In this paper, by introducing the "multi-label scale" and hybridizing the information of gene
Xuan Xiao, Zhi-Cheng Wu, Kuo-Chen Chou
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Mechanical Fractionation of Cultured Neuronal Cells into Cell Body and Neurite Fractions
Bio-Protocol, 2021 Many cells contain spatially defined subcellular regions that perform specialized tasks enabled by localized proteins. The subcellular distribution of these localized proteins is often facilitated by the subcellular localization of the RNA molecules that
Ankita Arora +3 more
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LOCATE: a mouse protein subcellular localization database [PDF]
Nucleic Acids Research, 2006 We present here LOCATE, a curated, web-accessible database that houses data describing the membrane organization and subcellular localization of proteins from the FANTOM3 Isoform Protein Sequence set. Membrane organization is predicted by the high-throughput, computational pipeline MemO. The subcellular locations of selected proteins from this set were
J. Lynn Fink +10 more
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Functional Segments on Intrinsically Disordered Regions in Disease-Related Proteins
Biomolecules, 2019 One of the unique characteristics of intrinsically disordered proteins (IPDs) is the existence of functional segments in intrinsically disordered regions (IDRs).
Hiroto Anbo +3 more
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PSI: a comprehensive and integrative approach for accurate plant subcellular localization prediction. [PDF]
PLoS ONE, 2013 Predicting the subcellular localization of proteins conquers the major drawbacks of high-throughput localization experiments that are costly and time-consuming. However, current subcellular localization predictors are limited in scope and accuracy.
Lili Liu +3 more
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Protein-protein interaction as a predictor of subcellular location [PDF]
BMC Systems Biology, 2009 AbstractBackgroundMany biological processes are mediated by dynamic interactions between and among proteins. In order to interact, two proteins must co-occur spatially and temporally. As protein-protein interactions (PPIs) and subcellular location (SCL) are discoveredviaseparate empirical approaches, PPI and SCL annotations are independent and might ...
Chang Shin +3 more
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Horticulturae, 2022 Ca2+-sensors, calcineurin B-like proteins (CBLs), and calcineurin B-like protein-interacting protein kinases (CIPKs) form a CBL–CIPK complex to regulate signal transduction.
Cuiyu Liu +7 more
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Prediction of membrane protein types and subcellular locations [PDF]
Proteins: Structure, Function, and Genetics, 1999 Membrane proteins are classified according to two different schemes. In scheme 1, they are discriminated among the following five types: (1) type I single-pass transmembrane, (2) type II single-pass transmembrane, (3) multipass transmembrane, (4) lipid chain-anchored membrane, and (5) GPI-anchored membrane proteins.
K C, Chou, D W, Elrod
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Traffic : the International Journal of Intracellular Transport, 2019 G protein‐coupled receptors (GPCRs) physically connect extracellular information with intracellular signal propagation. Membrane trafficking plays a supportive role by “bookending” signaling events: movement through the secretory pathway delivers GPCRs ...
Braden T. Lobingier, M. von Zastrow
semanticscholar +1 more source
DeepLoc 2.0: multi-label subcellular localization prediction using protein language models
Nucleic Acids Res., 2022 The prediction of protein subcellular localization is of great relevance for proteomics research. Here, we propose an update to the popular tool DeepLoc with multi-localization prediction and improvements in both performance and interpretability.
Vineet Thumuluri +4 more
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