Results 21 to 30 of about 4,838,802 (318)

Disparate subcellular location of putative sortase substrates in Clostridium difficile [PDF]

open access: yesScientific Reports, 2017
Clostridium difficile is a gastrointestinal pathogen but how the bacterium colonises this niche is still little understood. Sortase enzymes covalently attach specific bacterial proteins to the peptidoglycan cell wall and are often involved in ...
Johann Peltier   +3 more
doaj   +2 more sources

Location, location, location: subcellular protein partitioning in proteostasis and aging [PDF]

open access: yesBiophysical Reviews, 2021
AbstractSomatic maintenance and cell survival rely on proper protein homeostasis to ensure reliable functions across the cell and to prevent proteome collapse. Maintaining protein folding and solubility is central to proteostasis and is coordinated by protein synthesis, chaperoning, and degradation capacities.
Anita V. Kumar, Louis R. Lapierre
openaire   +2 more sources

Function of AtGST8 gene and response of its over-expressed plants to MV stress in Arabidopsis thaliana

open access: yesNantong Daxue xuebao. Ziran kexue ban, 2023
Reduced glutathione(GSH) is connected to the substrate under the catalysis of glutathione S-transferase(GST) to form a water-soluble product. When plants are stressed, GST will induce expression to protect plants from damage and play an important role in
WANG Lingjuan; LU Shuai; GAO Cong; HAN Binying; ZHAO Chenglei; XUE Penghui; CAO Yunying
doaj   +1 more source

Protein subcellular location prediction [PDF]

open access: yesProtein Engineering, Design and Selection, 1999
The function of a protein is closely correlated with its subcellular location. With the rapid increase in new protein sequences entering into data banks, we are confronted with a challenge: is it possible to utilize a bioinformatic approach to help expedite the determination of protein subcellular locations?
K C, Chou, D W, Elrod
openaire   +2 more sources

Using Evolutionary Information and Multi-Label Linear Discriminant Analysis to Predict the Subcellular Location of Multi-Site Bacterial Proteins via Chou’s 5-Steps Rule

open access: yesIEEE Access, 2020
The function of a protein is closely tied to its subcellular location. Identifying the subcellular location of proteins is a crucial step to understand their functions.
Lei Du   +3 more
doaj   +1 more source

Density Distribution Maps: A Novel Tool for Subcellular Distribution Analysis and Quantitative Biomedical Imaging

open access: yesSensors, 2021
Subcellular spatial location is an essential descriptor of molecules biological function. Presently, super-resolution microscopy techniques enable quantification of subcellular objects distribution in fluorescence images, but they rely on instrumentation,
Ilaria De Santis   +4 more
doaj   +1 more source

Paeans/subcellular: Subcellular localization

open access: yes, 2021
First release of protein subcellular location prediction ...
Pan Gaofeng
core   +1 more source

Design powerful predictor for mRNA subcellular location prediction in Homo sapiens

open access: yesBriefings Bioinform., 2020
Messenger RNAs (mRNAs) shoulder special responsibilities that transmit genetic code from DNA to discrete locations in the cytoplasm. The locating process of mRNA might provide spatial and temporal regulation of mRNA and protein functions.
Zhao-Yue Zhang   +5 more
semanticscholar   +1 more source

Multi-class subcellular location prediction for bacterial proteins [PDF]

open access: yes, 2006
Two algorithms, based onBayesian Networks (BNs), for bacterial subcellular location prediction, are explored in this paper: one predicts all locations for Gram+ bacteria and the other all locations for Gram- bacteria.
Taylor, Paul D.   +2 more
core   +6 more sources

Dual-Signal Feature Spaces Map Protein Subcellular Locations Based on Immunohistochemistry Image and Protein Sequence

open access: yesSensors, 2023
Protein is one of the primary biochemical macromolecular regulators in the compartmental cellular structure, and the subcellular locations of proteins can therefore provide information on the function of subcellular structures and physiological ...
Kai Zou   +4 more
doaj   +1 more source

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