The subcellular location of selenoproteins and the impact on their function. [PDF]
Nutrients, 2015 Most human selenium containing proteins contain selenium in the form of the amino acid selenocysteine, which is encoded in the corresponding mRNA as a UGA codon.
Diamond AM.
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HAR_Locator: a novel protein subcellular location prediction model of immunohistochemistry images based on hybrid attention modules and residual units [PDF]
Frontiers in Molecular Biosciences, 2023 Introduction: Proteins located in subcellular compartments have played an indispensable role in the physiological function of eukaryotic organisms. The pattern of protein subcellular localization is conducive to understanding the mechanism and function ...
Kai Zou +5 more
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LncLocation: Efficient Subcellular Location Prediction of Long Non-Coding RNA-Based Multi-Source Heterogeneous Feature Fusion. [PDF]
Int J Mol Sci, 2020 Recent studies uncover that subcellular location of long non-coding RNAs (lncRNAs) can provide significant information on its function. Due to the lack of experimental data, the number of lncRNAs is very limited, experimentally verified subcellular ...
Feng S, Liang Y, Du W, Lv W, Li Y.
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Improving Protein Subcellular Location Classification by Incorporating Three-Dimensional Structure Information [PDF]
Biomolecules, 2021 The subcellular locations of proteins are closely related to their functions. In the past few decades, the application of machine learning algorithms to predict protein subcellular locations has been an important topic in proteomics.
Ge Wang +3 more
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IEEE/ACM Transactions on Computational Biology & Bioinformatics, 2020 Prediction of protein subcellular location has currently become a hot topic because it has been proven to be useful for understanding both the disease mechanisms and novel drug design.
Guanghui Liu +5 more
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Subcellular Singlet Oxygen and Cell Death: Location Matters
Frontiers in Chemistry, 2020 We developed a tool for targeted generation of singlet oxygen using light activation of a genetically encoded fluorogen-activating protein complexed with a unique dye molecule that becomes a potent photosensitizer upon interaction with the protein.
Pingping Liang +9 more
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Euglena Central Metabolic Pathways and Their Subcellular Locations [PDF]
Metabolites, 2019 Euglenids are a group of algae of great interest for biotechnology, with a large and complex metabolic capability. To study the metabolic network, it is necessary to know where the component enzymes are in the cell, but despite a long history of research
Sahutchai Inwongwan +3 more
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Fluorescence Intensity of Protein Tags Is Dependent on Their Subcellular Location [PDF]
CellsFluorescent protein (FP) tagging is widely used in imaging experiments to investigate the subcellular distribution of proteins. However, because the fluorescence of most FP chromophores is quenched upon their protonation, their fluorescence intensities ...
Yan Chen +4 more
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Accurate prediction of subcellular location of apoptosis proteins combining Chou's PseAAC and PsePSSM based on wavelet denoising. [PDF]
Oncotarget, 2017 Apoptosis proteins subcellular localization information are very important for understanding the mechanism of programmed cell death and the development of drugs.
Yu B +7 more
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Prediction of subcellular location of apoptosis proteins by incorporating PsePSSM and DCCA coefficient based on LFDA dimensionality reduction. [PDF]
BMC Genomics, 2018 Apoptosis is associated with some human diseases, including cancer, autoimmune disease, neurodegenerative disease and ischemic damage, etc. Apoptosis proteins subcellular localization information is very important for understanding the mechanism of ...
Yu B +6 more
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