Results 71 to 80 of about 4,838,802 (318)
Identified proteins according to the subcellular location.
, 2019 Percentage of relatively quantified proteins more abundant A) in clone R17-12 C1 and B) in clone P178-13 C7 when compared to each other, classified according to their subcellular location.
Ivana Bilic (162631) +7 more
core +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Evidence for the adaptation of protein pH-dependence to subcellular pH
BMC Biology, 2009 Background The availability of genome sequences, and inferred protein coding genes, has led to several proteome-wide studies of isoelectric points. Generally, isoelectric points are distributed following variations on a biomodal theme that originates ...
Warwicker Jim, Chan Pedro
doaj +1 more source
Leaping into the Unknown World of Sporisorium scitamineum Candidate Effectors
Journal of Fungi, 2020 Sporisorium scitamineum is a biotrophic fungus causing sugarcane smut disease. In this study, we set up a pipeline and used genomic and dual transcriptomic data previously obtained by our group to identify candidate effectors of S.
Natália Sousa Teixeira-Silva +6 more
doaj +1 more source
JEPSLD: a judgmental eukaryotic protein subcellular location database
, 2013 Shatkay, HagitProteins play a key role in every biological process. Moreover, they localize to specific compartments or organelles within the cell.
Patra, Sanjeev
core +1 more source
Alkaline phosphatase fusions: sensors of subcellular location [PDF]
Journal of Bacteriology, 1990 Alkaline phosphatase fusions allow genes to be identified solely on the basis of their protein products being exported from the cytoplasm. Thus, the use of such fusions helps render biological processes which involve cell envelope and secreted proteins accessible to a sophisticated genetic analysis. Furthermore, alkaline phosphatase fusions can be used
C, Manoil, J J, Mekalanos, J, Beckwith
openaire +2 more sources
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
The distribution of biological functions (A) and subcellular location (B) of identified proteins.
, 2015 The distribution of biological functions (A) and subcellular location (B) of identified proteins.
Kasper Hettinga (352565) +5 more
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source