Results 11 to 20 of about 7,181 (165)

Subclinical depressive symptoms and continued cannabis use: predictors of negative outcomes in first episode psychosis. [PDF]

PLoS ONE, 2015
Although depressive symptoms in first episode psychosis have been associated with cannabis abuse, their influence on the long-term functional course of FEP patients who abuse cannabis is unknown.
Itxaso González-Ortega, Susana Alberich, Enrique Echeburúa, Felipe Aizpuru, Eduardo Millán, Eduard Vieta, Carlos Matute, Ana González-Pinto   +7 more
doaj   +6 more sources

Socioemotional mechanisms of loneliness in subclinical psychosis. [PDF]

Schizophr Res, 2021
Loneliness is an important predictor of physical and mental health in the general population and in individuals across the psychosis spectrum, including those experiencing subclinical psychotic-like experiences (PLEs). However, the mechanisms underlying loneliness in the psychosis spectrum are not well understood.
Leathem LD, Currin DL, Montoya AK, Karlsgodt KH.   +3 more
europepmc   +5 more sources

Genetic and psychosocial stressors have independent effects on the level of subclinical psychosis: findings from the multinational EU-GEI study. [PDF]

Epidemiol Psychiatr Sci, 2022
Abstract Aims Gene x environment (G×E) interactions, i.e. genetic modulation of the sensitivity to environmental factors and/or environmental control of the gene expression, have not been reliably established regarding aetiology of psychotic disorders.
Pignon B, Peyre H, Ayrolles A, Kirkbride JB, Jamain S, Ferchiou A, Richard JR, Baudin G, Tosato S, Jongsma H, de Haan L, Tarricone I, Bernardo M, Velthorst E, Braca M, Arango C, Arrojo M, Bobes J, Del-Ben CM, Di Forti M, Gayer-Anderson C, Jones PB, La Cascia C, Lasalvia A, Menezes PR, Quattrone D, Sanjuán J, Selten JP, Tortelli A, Llorca PM, van Os J, Rutten BPF, Murray RM, Morgan C, Leboyer M, Szöke A, Schürhoff F.   +36 more
europepmc   +16 more sources

Evidence for a Shared Etiological Mechanism of Psychotic Symptoms and Obsessive-Compulsive Symptoms in Patients with Psychotic Disorders and Their Siblings. [PDF]

PLoS ONE, 2015
The prevalence of obsessive-compulsive disorder in subjects with psychotic disorder is much higher than in the general population. The higher than chance co-occurrence has also been demonstrated at the level of subclinical expression of both phenotypes ...
Marije Swets, Frank Van Dael, Sabine Roza, Robert Schoevers, Inez Myin-Germeys, Lieuwe de Haan, Genetic Risk and Outcome of Psychosis (GROUP) investigators   +6 more
doaj   +1 more source

O2.3. ABNORMAL BRAIN AGING IN YOUTH WITH SUBCLINICAL PSYCHOSIS AND OBSESSIVE-COMPULSIVE SYMPTOMS [PDF]

Schizophr Bull, 2020
Abstract Background Psychiatric symptoms in childhood and adolescence have been associated with both delayed and accelerated patterns of grey matter development. This suggests that deviation in brain structure from a normative range of variation for a given age might be important in the emergence of ...
Cropley V, Tian Y, Fernando K, Mansour S, Pantelis C, Cocchi L, Zalesky A.   +6 more
europepmc   +4 more sources

A Population Based Analysis of Subclinical Psychosis and Help-Seeking Behavior [PDF]

Schizophrenia Bulletin, 2010
Clinically defined psychosis is recognizable and distinguishable from nonclinical or subclinical psychosis by virtue of its clinical relevance (ie, its associated distress and its need for care and/or treatment). According to the continuum hypothesis, subclinical psychosis is merely quantitatively different from more extreme phenotypic expressions and ...
Jamie, Murphy, Mark, Shevlin, James, Houston, Gary, Adamson   +3 more
openaire   +2 more sources

Being psychotic is not necessarily being ill: Psychotic continuum and the relevance of lacanian psychoanalytic approach

European Psychiatry, 2021
Introduction The notion of subclinical psychosis is as old as Eugen Bleuler’s work on schizophrenia. It is also consistent with psychodynamic theories (see PDM-2) on the organization of personality on different levels including, among others, a ...
G. Mitropoulos
doaj   +1 more source

Gradients of striatal function in antipsychotic-free first-episode psychosis and schizotypy

Translational Psychiatry, 2023
Both psychotic illness and subclinical psychosis-like experiences (PLEs) have been associated with cortico-striatal dysfunction. This work has largely relied on a discrete parcellation of the striatum into distinct functional areas, but recent evidence ...
Marianne Oldehinkel, Jeggan Tiego, Kristina Sabaroedin, Sidhant Chopra, Shona M. Francey, Brian O’Donoghue, Vanessa Cropley, Barnaby Nelson, Jessica Graham, Lara Baldwin, Hok Pan Yuen, Kelly Allott, Mario Alvarez-Jimenez, Susy Harrigan, Christos Pantelis, Stephen J. Wood, Patrick McGorry, Mark A. Bellgrove, Alex Fornito   +18 more
doaj   +1 more source

Inequality and barriers in psychosis prevention: A systematic review on clinical high-risk for psychosis studies from developing countries

Frontiers in Psychiatry, 2023
BackgroundThe clinical high-risk for psychosis (CHR) paradigm is one of the best studied preventive paradigms in psychiatry. However, most studies have been conducted in high-income countries. It is unclear if knowledge from such countries applies to low
Alexandre Andrade Loch, Alexandre Andrade Loch, Ana Caroline Lopes-Rocha, Feten Fekih-Romdhane, Feten Fekih-Romdhane, Martinus Theodorus van de Bilt, Martinus Theodorus van de Bilt, Gonzalo Salazar de Pablo, Gonzalo Salazar de Pablo, Gonzalo Salazar de Pablo, Gonzalo Salazar de Pablo, Paolo Fusar-Poli, Paolo Fusar-Poli, Paolo Fusar-Poli   +13 more
doaj   +1 more source

The identification of family subtype based on the assessment of subclinical levels of psychosis in relatives [PDF]

BMC Psychiatry, 2012
Schizophrenia is a complex psychiatric disorder characterized by high phenotypic heterogeneity. Previous studies have distinguished between familial and sporadic forms of schizophrenia and have suggested clinical differentiation between patients and relatives from sporadic and multiplex families.
Derks, Eske M., Boks, Marco P. M., Vermunt, Jeroen K., Kahn, René S., Linszen, Don H., van Os, Jim, Wiersma, Durk, Bruggeman, Richard, Cahn, Wiepke, de Haan, Lieuwe, Krabbendam, Lydia, Myin-Germeys, Inez   +11 more
openaire   +6 more sources