Results 81 to 90 of about 198,597 (212)

Subclinical hypomania, psychiatric and neurodevelopmental diagnoses: phenotypic and aetiological overlap

Journal of Child Psychology and Psychiatry, EarlyView.
Background Subclinical hypomanic symptoms are fairly common in the general population but are linked to psychiatric and neurodevelopmental conditions. However, the genetic and environmental origins of these associations are unclear. This twin study examined the phenotypic and aetiological associations between subclinical hypomania and psychiatric and ...
Georgina M. Hosang, Miriam I. Martini, Angelica Ronald, Henrik Larsson, Sebastian Lundström, Paul Lichtenstein, Mark J. Taylor   +6 more
wiley   +1 more source

Differential efficacy of lithium and carbamazepine in the prophylaxis of bipolar disorder: Results of the MAP study [PDF]

, 2000
In a randomized clinical trial with an observation period of 2.5 years, the differential efficacy of lithium versus carbamazepine was compared in 171 bipolar patients (DSM-IV).
Greil, Waldemar, Kleindienst, Nikolaus
core   +1 more source

Disorders of Arousal in Children and Associated Emotional–Behavioural Problems: Results From a Non‐Clinical Longitudinal Cohort

Journal of Sleep Research, EarlyView.
This study reports associations between more frequent episodes of disorders of arousal at 4 years old and emotional–behavioural problems at age 4 and externalising problems at age 5. More frequent episodes seem to indicate more severe presentation and, thus, may be a warning sign for emotional–behavioural problems.
Christine Laganière, Hélène Gaudreau, Samantha Kenny, Michael Meaney, Marie‐Hélène Pennestri   +4 more
wiley   +1 more source

Models of Dynamic Belief Updating in Psychosis—A Review Across Different Computational Approaches

Frontiers in Psychiatry, 2022
To understand the dysfunctional mechanisms underlying maladaptive reasoning of psychosis, computational models of decision making have widely been applied over the past decade.
Teresa Katthagen, Sophie Fromm, Sophie Fromm, Sophie Fromm, Lara Wieland, Lara Wieland, Lara Wieland, Florian Schlagenhauf, Florian Schlagenhauf, Florian Schlagenhauf, Florian Schlagenhauf   +10 more
doaj   +1 more source

Psychosis-inducing effects of cannabis are related to both childhood abuse and COMT genotypes [PDF]

, 2014
OBJECTIVE: To test whether the association between childhood abuse, cannabis use and psychotic experiences (PEs) was moderated by the COMT (catechol-O-methyltransferase) gene.
Alemany, Silvia, Arias, Barbara, Fatjó-Vilas, Mar, Fañanás Saura, Lourdes, Gastó, Cristóbal, Ibáñez, Manuel I, Moya-Higueras, Jorge, Ortet, Generós, Villa Martín, Elena   +8 more
core   +1 more source

Daily Predictors of Psychotic‐Like Experiences in Older Adults: The Role of Sleep Quality, Negative Emotions, and Cognitive Failures

Journal of Sleep Research, EarlyView.
ABSTRACT Psychotic‐like experiences are subclinical psychotic symptoms that are usually accompanied by sleep problems, negative emotions, and poorer cognitive functioning. However, their night‐to‐day associations remain understudied in older adults. 72 participants aged 50–79 took part in a home‐based sleep study.
Vivien Tomacsek, Noémi Báthori, Miha Likar, Petra Hermann, Zoltán Vidnyánszky, Péter Simor   +5 more
wiley   +1 more source

White noise speech illusions in the general population: The association with psychosis expression and risk factors for psychosis.

PLoS ONE, 2019
IntroductionPositive psychotic experiences are associated with increased rate of white noise speech illusions in patients and their relatives. However, findings have been conflicting to what degree speech illusions are associated with subclinical ...
E Schepers, J van Os, R Lousberg
doaj   +1 more source

Psychotic-Like Experiences at the Healthy End of the Psychosis Continuum

Frontiers in Psychology, 2017
There is increasing evidence pointing toward a continuous distribution of psychotic symptoms and accompanying factors between subclinical and clinical populations.
Lui Unterrassner, Thomas A. Wyss, Diana Wotruba, Vladeta Ajdacic-Gross, Helene Haker, Helene Haker, Wulf Rössler, Wulf Rössler, Wulf Rössler   +8 more
doaj   +1 more source

Psychosis risk among pregnant women in Ghana.

PLoS ONE, 2022
IntroductionPsychotic illness, although is rare, has been reported in the perinatal period. Individuals diagnosed with psychotic illness tend to first exhibit psychotic-like experiences (PLEs), defined as subclinical psychotic symptoms that occur outside
Samuel Adjorlolo, Gwendolyn Mensah, Caroline Dinam Badzi   +2 more
doaj   +1 more source

Association Between Levels of the Acute Phase Proteins Alpha‐1‐Acid Glycoprotein and C‐Reactive Protein and Serum Concentrations of Clozapine: A Study of 1106 Therapeutic Drug Monitoring Samples

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Several publications have reported elevated clozapine concentrations in patients experiencing infections or inflammatory reactions. Proposed mechanisms include increased levels of pro‐inflammatory cytokines that may inhibit clozapine metabolism and enhanced binding of clozapine to the acute phase protein alpha‐1‐acid glycoprotein (AGP).
Ketil Arne Espnes, Olav Spigset, Guro Emilie Bratt, Marit Tilrem, Sarita Hamnes, Eirik Skogvoll, Ragnhild Bergene Skråstad   +6 more
wiley   +1 more source