Results 101 to 110 of about 141,920 (285)

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

open access: yesAdvanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu   +8 more
wiley   +1 more source

Masculinity, Sexuality and the Visual Culture of Glam Rock [PDF]

open access: yes, 2002
Glam Rock. a musical style accompanied by a flamboyant dress code emerged during the early 1970s. This essay looks at the changing representations of masculinity which occured during the late 1960s and early 1970s.
Gregory, Georgina
core  

Coincident Fluorescence‐Burst Analysis of Actin Cargo Molecules in Secreted Single Diffusing Extracellular Vesicles From Human Induced Pluripotent Stem Cells

open access: yesAdvanced Science, EarlyView.
This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen   +4 more
wiley   +1 more source

Street(icono)clashes. Blu vs. Genus Bononiae: un caso di iconoclastia urbana

open access: yesOcula, 2017
Moving from a perspective of semiotics of culture, the article investigates the events which accompanied Banksy and Co: Art in the Urban Form, the exhibition held in the City Museum of Bologna in May 2016, with a special attention to the reaction of the ...
Francesco Mazzucchelli
doaj   +1 more source

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

open access: yesAdvanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo   +3 more
wiley   +1 more source

“I am a rogue night elf”: Avatars, gaming and The Big Bang Theory [PDF]

open access: yesG|A|M|E The Italian Journal of Game Studies, 2014
CBS’s The Big Bang Theory (TBBT) frequently exhibits elements of video games and gaming culture. The author uses subculture theory to consider the representation of video games, gamers, and their avatars within popular culture.
Theo Plothe
doaj  

Resistance through style: Antonio and Tom of Finland [PDF]

open access: yes, 2014
An article about political subtexts and strategies in Antonio's fashion illustrations and the political and cultural impact of Tom of Finland's ...
Taylor, Zoe
core  

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

open access: yesAdvanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li   +10 more
wiley   +1 more source

Language, Culture and Symbolic Forms [PDF]

open access: yes, 2010
As Ernst Cassierer introduced in his “Philosophie der symbolischen Formen” in 1923, he specifically mentioned “language” as well as a way of symbolic forms.
Theis, Wolfgang
core  

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

open access: yesAdvanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang   +7 more
wiley   +1 more source

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