Results 11 to 20 of about 977,117 (291)

Effect of fixed-dose subcutaneous reslizumab on asthma exacerbations in patients with severe uncontrolled asthma and corticosteroid sparing in patients with oral corticosteroid-dependent asthma : results from two phase 3, randomised, double-blind, placebo-controlled trials [PDF]

, 2020
BACKGROUND: Reslizumab 3 mg/kg administered intravenously is approved for the treatment of severe eosinophilic asthma. We assessed the safety and efficacy of subcutaneous reslizumab 110 mg in two trials in patients with uncontrolled severe asthma and ...
Adir, Yochai, Bernstein, Jonathan A, Brusselle, Guy, Castro, Mario, Garin, Margaret, Hickey, Lisa, Humbert, Marc, Jacobs, Joshua, Marsteller, Douglas A, Maspero, Jorge Fernando, McElhattan, Jennifer, Murphy, Kevin, Vanlandingham, Rebecca, Virchow, J Christian   +13 more
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The Sex and Race Specific Relationship between Anthropometry and Body Fat Composition Determined from Computed Tomography: Evidence from the Multi-Ethnic Study of Atherosclerosis. [PDF]

, 2015
BackgroundFew studies have investigated the relationship of anthropometric measurements with computed tomography (CT) body fat composition, and even fewer determined if these relationships differ by sex and race.MethodsCT scans from 1,851 participants in
Allison, Matthew A, Anderson, Cheryl AM, Ding, Jingzhong, Golden, Sherita Hill, Mongraw-Chaffin, Morgana, Ouyang, Pamela, Schreiner, Pamela J, Szklo, Moyses, Woodward, Mark, Young, Jeffery Hunter   +9 more
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Subcutaneous emphysema during root canal therapy: endodontic accident by sodium hypoclorite [PDF]

, 2017
Cervicofacial subcutaneous emphysema is defined as the abnormal introduction of air in the subcutaneous tissues of the head and neck. It is mainly caused by trauma, head and neck surgery, general anesthesia, and coughing or habitual performance of ...
Battisti, Andrea, Ciolfi, Chiara, Mohsen, Mohamed, Palaia, Gaspare, Romeo, Umberto, Tenore, Gianluca   +5 more
core   +1 more source

Total Parathyroidectomy with Subcutaneous Parathyroid Forearm Autotransplantation in the Treatment of Secondary Hyperparathyroidism: A Single-Center Experience. [PDF]

, 2018
Introduction Secondary hyperparathyroidism is common in chronic kidney disease. Parathyroidectomy is indicated in refractory hyperparathyroidism when medical treatments and so the parathyroid hormone levels cannot be lowered to acceptable values without
Casella, Claudio, Dimko, Mira, Galani, Alessandro, Lai, Silvia, Ministrini, Silvia, Nazario Portolani, And, Totaro, Luigi   +6 more
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In preeclampsia, maternal third trimester subcutaneous adipocyte lipolysis is more resistant to suppression by insulin than in healthy pregnancy [PDF]

, 2014
Obesity increases preeclampsia risk, and maternal dyslipidemia may result from exaggerated adipocyte lipolysis. We compared adipocyte function in preeclampsia with healthy pregnancy to establish whether there is increased lipolysis.
Forrest, Rachel., Freeman, Dilys J., Huda, Shahzya S., Jordan, Fiona, Paterson, Nicole, Sattar, Naveed   +5 more
core   +1 more source

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models. [PDF]

, 2014
The aim of the present study was to examine the efficacy of tumor-targeting Salmonella typhimurium A1-R treatment following anti-vascular endothelial growth factor (VEGF) therapy on VEGF-positive human pancreatic cancer.
Bouvet, Michael, Chishima, Takashi, Endo, Itaru, Hiroshima, Yukihiko, Hoffman, Robert M, Ichikawa, Yasushi, Maawy, Ali, Matsuyama, Ryusei, Miwa, Shinji, Momiyama, Masashi, Mori, Ryutaro, Murakami, Takashi, Sato, Sho, Tanaka, Kuniya, Yamamoto, Mako, Yano, Shuya, Zhang, Yong, Zhao, Ming   +17 more
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New insight into the importance of formulation variables on parenteral growth hormone preparations: potential effect on the injection-site pain

Frontiers in Endocrinology, 2022
Reducing injection-site pain (ISP) in patients with chronic conditions such as growth hormone deficiency is a valuable strategy to improve patient compliance and therapeutic efficiency.
Bita Taghizadeh, Mahmoud Reza Jaafari, Mahmoud Reza Jaafari, Nosratollah Zarghami, Nosratollah Zarghami   +4 more
doaj   +1 more source

Development of a Biodegradable Subcutaneous Implant for Prolonged Drug Delivery Using 3D Printing

Pharmaceutics, 2020
Implantable drug delivery devices offer many advantages over other routes of drug delivery. Most significantly, the delivery of lower doses of drug, thus, potentially reducing side-effects and improving patient compliance. Three dimensional (3D) printing
Sarah A. Stewart, Juan Domínguez-Robles, Victoria J. McIlorum, Elena Mancuso, Dimitrios A. Lamprou, Ryan F. Donnelly, Eneko Larrañeta   +6 more
doaj   +1 more source

Needle-Free Jet Injectors and Nanosuspensions: Exploring the Potential of an Unexpected Pair

Pharmaceutics, 2022
Needle-free liquid jet injectors are medical devices used to administer pharmaceutical solutions through the skin. Jet injectors generate a high-speed stream of liquid medication that can puncture the skin and deliver the drug to the underlying tissues ...
Michele Schlich, Luca Casula, Aurora Musa, Rosa Pireddu, Giulia Pitzanti, Maria Cristina Cardia, Donatella Valenti, Salvatore Marceddu, Anna Maria Fadda, Maria Antonietta De Luca, Chiara Sinico, Francesco Lai   +11 more
doaj   +1 more source

Use of apomorphine in Parkinsonian patients with neuropsychiatric complications to oral treatment [PDF]

, 1997
Neuropsychiatric side effects often complicate anti-Parkinsonian therapy and pose a significant problem in the optimal management of idiopathic Parkinson's disease.
Abbott, R.J., Chaudhuri, K.R., Ellis, C, Leigh, P.N., Lemmens, Gilbert, Parkes, J.D., Pye, I.F.   +6 more
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