Optimizing adipogenic transdifferentiation of bovine mesenchymal stem cells: a prominent role of ascorbic acid in FABP4 induction [PDF]
Adipocyte differentiation of bovine adipose-derived stem cells (ASC) was induced by foetal bovine serum (FBS), biotin, pantothenic acid, insulin, rosiglitazone, dexamethasone and 3-isobutyl-1-methylxanthine, followed by incubation in different media to ...
Aschenbach, Jörg R. +6 more
core +1 more source
Subcutaneous dirofilariasis in children—An emerging zoonotic nematodal infection: A case series
Key clinical Message Human subcutaneous dirofilariasis is an infection caused by filarial worms. Due to the recent rise of human disease, it is considered as an emerging zoonosis. Most of the cases in children recorded in India had ocular infection; very
K. O. Varghese Tharakan +4 more
doaj +1 more source
BACKGROUND: Newer research comparing routes of medication administration has extended beyond efficacy as a primary endpoint to incorporate patient preference.
Sophia A. Cordes, BS +4 more
doaj +1 more source
Lymphoma presenting as subcutaneous periorbital nodules
A 67-year-old female presented with a several month history of painless enlarging right periorbital growths. Examination showed multiple nontender subcutaneous nodules superior to the right eyebrow.
Lauren N DeMaria +2 more
doaj +1 more source
Innate Immunity in Calcinosis Cutis
Calcinosis cutis is the deposition of calcium salts in the skin and subcutaneous tissue, manifesting as variably shaped papules, nodules, and plaques that can substantially impair quality of life.
Simon W. Jiang +2 more
doaj +1 more source
Pre-B-cell acute lymphoblastic leukemia with bulk extramedullary disease and chromosome 22 (EWSR1) rearrangement masquerading as Ewing sarcoma [PDF]
We report a 2-year-old female with a subcutaneous tumor who was initially misdiagnosed as suffering from Ewing sarcoma with a positive EWSR1 rearrangement and EWS/FLI1 transcript.
Jakovljević, Gordana +6 more
core +1 more source
A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis. [PDF]
The search for effective treatments for obesity and its comorbidities is of prime importance. We previously identified IKK-ε and TBK1 as promising therapeutic targets for the treatment of obesity and associated insulin resistance. Here we show that acute
Ahmadian, Maryam +16 more
core +2 more sources
Effect of ACADL on the differentiation of goat subcutaneous adipocyte [PDF]
Objective The aim of this study was to clone the mRNA sequence of the Acyl-CoA dehydrogenase long chain (ACADL) gene of goats and explore the effect of ACADL on the differentiation of subcutaneous fat cells on this basis.
A Li +8 more
doaj +1 more source
In Vivo Imaging of Transplanted Islets with ^(64)Cu-DO3A-VS-Cys^(40)-Exendin-4 by Targeting GLP-1 Receptor [PDF]
Glucagon-like peptide 1 receptor (GLP-1R) is highly expressed in pancreatic islets, especially on β-cells. Therefore, a properly labeled ligand that binds to GLP-1R could be used for in vivo pancreatic islet imaging.
Bading, James R. +11 more
core +2 more sources
Ethnic differences in adiposity and diabetes risk – insights from genetic studies [PDF]
Type 2 diabetes is more common in non-Europeans and starts at a younger age and at lower BMI cut-offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of disease with a focus on the role of
Bell, J.D. +7 more
core +2 more sources

