Results 131 to 140 of about 1,346,803 (378)
Advanced Science, EarlyView.This study identifies fatty acid desaturase 2 (FADS2) as a key regulator linking polyunsaturated fatty acid (PUFA) metabolism to psoriatic inflammation. FADS2 deficiency impairs docosahexaenoic acid (DHA) biosynthesis, enhances NF‐κB signaling, and promotes neutrophil‐driven skin inflammation. PPARα transcriptionally activates FADS2, and its activation
Jiangluyi Cai +19 more
wiley +1 more source
The Chemical Nature of the Subcutaneous Fat in the Normal and Sclerematous Infant [PDF]
, 1926 Harold John Channon, G.A. Harrison
openalex +1 more source
Noggin depletion in adipocytes promotes obesity in mice. [PDF]
, 2019 ObjectiveObesity has increased to pandemic levels and enhanced understanding of adipose regulation is required for new treatment strategies. Although bone morphogenetic proteins (BMPs) influence adipogenesis, the effect of BMP antagonists such as Noggin ...
Blázquez-Medela, Ana M +14 more
core +1 more source
Okanin Suppresses the Growth of Colorectal Cancer Cells by Targeting at Peroxiredoxin 5
Advanced Science, EarlyView.Okanin suppresses colorectal cancer growth by directly targeting PRDX5. This natural compound selectively binds peroxiredoxin 5 (PRDX5), inhibiting its activity and inducing WSB1‐mediated degradation. PRDX5 loss elevates ROS, suppresses GPX4 via SIAH2, and further triggers cell death (apoptosis and ferroptosis).
Ji Zhong Zhao +9 more
wiley +1 more source
BMC Public HealthBackground Cardiovascular diseases (CVDs) are the primary cause of mortality globally. The prevalence of obesity is rising worldwide; there seems to be a significant positive association between obesity and CVDs.
Hadi Emamat +5 more
doaj +1 more source
The distribution of subcutaneous and internal fat in man
Annals of Human Biology, 1986 Total body fat mass was estimated in 25 women and 21 men from densitometry. All subjects were apparently healthy. Subcutaneous fat mass was calculated by measuring subcutaneous fat thickness at 12 sites using A-mode ultrasound. The proportion of fat situated subcutaneously (PFSS) was found to vary considerably between individuals (range 0.50-0.97 in ...
Davies, P.S.W. +2 more
openaire +4 more sources
Advanced Science, EarlyView.Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang +9 more
wiley +1 more source
International Journal of Biological Sciences, 2009 We have found natural products exhibiting lipolysis-promoting activity in subcutaneous adipocytes, which are less sensitive to hormones than visceral adipocytes. The activities and a action mechanisms of a novel plant extract of Cirsium oligophyllum (CE)
Shinobu Mori, Mayumi Satou, Satoshi Kanazawa, Naonobu Yoshizuka, Tadashi Hase, Ichiro Tokimitsu, Yoshinori Takema, Yoshinori Nishizawa, Toshihiko Yada
doaj
Subcutaneous fat necrosis of the newborn
Indian Dermatology Online Journal, 2020 Mani Makhija +2 more
openaire +4 more sources
Production and carcass traits of high dairy genetic merit Holstein, standard dairy genetic merit Friesian and Charolais × Holstein-Friesian male cattle [PDF]
, 2005 peer-reviewedThe increased proportion of Holstein genetic material in the dairy herd has consequences for beef production in Ireland. A total of 72 spring-born male calves (24 Holsteins (HO), 24 Friesian (FR) and 24 Charolais × Holstein-Friesians (CH ...
Caffrey, Patrick J. +4 more
core