Results 151 to 160 of about 1,346,803 (378)

Effects of Acorns on Fatty Acid Composition and Lipid Metabolism in Adipose Tissue of Yuxi Black Pigs

Animals
The objective of the present research was the examination of how varying proportions of an acorn diet affects the deposition of subcutaneous fat and the composition of fatty acids (FAs) in Yuxi black pigs.
Zhe Sun, Dongyang Liu, Siyuan An, Xuejia Wu, Jinzhou Zhang, Zhiguo Miao   +5 more
doaj   +1 more source

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Targeting Multilayered Metabolic Networks in Brain Diseases: Emerging Perspectives on Nanodelivery Strategies

Advanced Science, EarlyView.
Brain diseases involve multilayered metabolic disruptions that reshape cellular interactions and microenvironments. This review outlines core metabolic features across disease states and presents emerging nanodelivery strategies as precision tools to reprogram pathological metabolism.
Jingyi Zhou, Chen Jiang
wiley   +1 more source

Effects of microcurrents and physical exercise on the abdominal fat: a randomized controlled trial in patients with coronary artery disease [PDF]

, 2015
Coronary artery disease are associated with decreased levels of physical activity, contributing to increases in abdominal fat and consequently the metabolic risk.
Albuquerque, Aníbal, Bastos, José Mesquita, Freitas, Carla Patrícia, Melo, Cristina, Noites, Andreia, Pinto, Joana, Ribeiro, Fernando, Teixeira, Madalena   +7 more
core  

STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer

Advanced Science, EarlyView.
This study demonstrates that STK25 depletion facilitates CRC immune escape through the inhibition of PD‐L1 Ser283 phosphorylation‐mediated ubiquitination, and promotes tumor growth. Furthermore, these findings identify STK25 as a potential therapeutic target to trigger antitumor immunity and promote immunotherapy efficacy. Abstract Tumor immune evasion
Xiaowen Qiao, Pu Xing, Hao Hao, Jiangbo Chen, Lin Song, Yifan Hou, Xinying Yang, Kai Weng, Jie Chen, Pin Gao, Tongkun Song, Hong Yang, Tianqi Liu, Yumeng Ran, Bo Chen, Wei Zhao, Jiabo Di, Zaozao Wang, Jun Zhang, Xiangqian Su, Beihai Jiang   +20 more
wiley   +1 more source

Influence of maternal obesity on subcutaneous fat in the newborn. [PDF]

, 1976
A G Whitelaw
openalex   +1 more source

Arginine Metabolic Disruption Impairs Hair Regeneration via ROS‐Mediated Inactivation of mTOR Signaling in Androgenetic Alopecia

Advanced Science, EarlyView.
Arginine deficiency accelerates androgenetic alopecia. Serum metabolome shows reduced circulating arginine, while local metabolic disruption depletes follicular reserves, triggering reactive oxygen species (ROS) accumulation and mTOR suppression that induce hair miniaturization.
Shixin Duan, Guo Li, Yanji Chu, Junbo Zhang, Li Yang, Yujin Zhang, Fangfen Liu, Jiayun Li, Mengting Chen, Ben Wang, Zhixiang Zhao, Wei Shi, Yiya Zhang, Guangtong Deng, Xinwei Kuang, Hongfu Xie, Yufan Cheng, Zhili Deng, Ji Li, Yan Tang   +19 more
wiley   +1 more source

Expression of Y2R mRNA Expression in Subcutaneous and Visceral Adipose Tissues Compared between Normal Weight and Obese Female Subjects

Siriraj Medical Journal, 2017
Y2R mRNA expression in subcutaneous and visceral fat tissues as well as serum PYY levels between obese and normal weight subjects.
Saimai Chatree, Malika Churintaraphan
doaj  

Demonstration of protein AA in subcutaneous fat tissue obtained by fine needle biopsy. [PDF]

, 1979
Per Westermark, Björn Stenkvist, J. B. Natvig, Elisabeth Olding-Stenkvist   +3 more
openalex   +1 more source

Targeting Methylglyoxal Metabolism to Enhance Ferroptosis Sensitivity in Tumor Therapy

Advanced Science, EarlyView.
This study reveals how blocking a detox enzyme called GLO1 increases the buildup of a toxic molecule, methylglyoxal (MGO), which triggers cancer cell death by ferroptosis. A protein called PJA1 drives this process. Targeting the PJA1–GLO1 pathway boosts the effectiveness of ferroptosis‐inducing treatments in tumors, offering a promising approach for ...
Xinyue Zhang, Leng Han, Zimu Wang, Hanghui Yu, Jiao Liu, Rui Kang, Daolin Tang, Zhengjia Liu, Xianlong Du, Enyong Dai   +9 more
wiley   +1 more source