A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao +16 more
wiley +1 more source
Internal Tissue Expansion Induces Outward Migration of ADSCs From the Subcutaneous Fat Flap to Promote Skin Regeneration of the Expanded Area. [PDF]
Tang H, Xue Z, Li Y, Dong Z, Liao Y.
europepmc +1 more source
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin +19 more
wiley +1 more source
Radiologic Evaluation of Subcutaneous Fat Necrosis Complicated by an Abscess in a Newborn: A Case Report. [PDF]
Al-Kharabsheh YE +4 more
europepmc +1 more source
Serum Retinol-Binding Protein Is More Highly Expressed in Visceral than in Subcutaneous Adipose Tissue and Is a Marker of Intra-abdominal Fat Mass [PDF]
Nora Klöting +10 more
openalex +1 more source
HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong +14 more
wiley +1 more source
Comparative Analyses of Gene and Protein Expressions and the Lipid Contents in Intramuscular and Subcutaneous Fat Tissues in Fattening Steers. [PDF]
Ji K, Yang M, Tan Z, Zhao H, Zhang X.
europepmc +1 more source
This study presents the first application of deuterium metabolic imaging (DMI) for assessing therapeutic response in bladder cancer. Employing [2,3,4,6,6′‐2H5]‐D‐glucose, DMI successfully identified chemotherapy‐induced suppression of glycolysis both in vitro and in vivo.
Lingmin Kong +15 more
wiley +1 more source
Association of point-of-care ultrasound-derived subcutaneous fat thickness with DXA-measured body fat percentage in older adults. [PDF]
Ganbat U +7 more
europepmc +1 more source

