Results 61 to 70 of about 6,650,813 (243)

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Identification of body fat tissues in MRI data [PDF]

, 2004
In recent years non-invasive medical diagnostic techniques have been used widely in medical investigations. Among the various imaging modalities available, Magnetic Resonance Imaging is very attractive as it produces multi-slice images where the contrast
Robinson, Kevin, Brennan, Darren, Sadleir, Robert J.T., Lynch, Michael, Ilea, Dana E., Ghita, Ovidiu, Whelan, Paul F.   +6 more
core   +2 more sources

Quantification of Abdominal Fat in Obese and Healthy Adolescents Using 3 Tesla Magnetic Resonance Imaging and Free Software for Image Analysis. [PDF]

PLoS ONE, 2017
BACKGROUND AND AIMSComputed tomography, which uses ionizing radiation and expensive software packages for analysis of scans, can be used to quantify abdominal fat.
Juliana Cristina Eloi, Matias Epifanio, Marília Maia de Gonçalves, Augusto Pellicioli, Patricia Froelich Giora Vieira, Henrique Bregolin Dias, Neide Bruscato, Ricardo Bernardi Soder, João Carlos Batista Santana, Marialena Mouzaki, Matteo Baldisserotto   +10 more
doaj   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

AVALIAÇÃO COMPARATIVA DA METODOLOGIA DE DETERMINAÇÃO DA ÁREA DE OLHO DE LOMBO EM SUÍNOS (Sus domesticus)

Ciência Animal Brasileira, 2011
In studies involving the carcass characteristics conducted at the Department of Animal Science of the Federal University of Piauí, the linear measurements of rib eye area (REA) and subcutaneous fat area (SFA) have been carried out by the plastic grid ...
MAURÍCIO DE PAULA FERREIRA TEIXEIRA, JULIANA FORTES VILARINHO BRAGA, MANOEL HENRIQUE KLEIN JÚNIOR, MÁRVIO LOBÃO TEIXEIRA ABREU   +3 more
doaj  

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Color doppler ultrasonography to evaluate hypoechoic areas in pressure ulcers: A report of two cases

Journal of Medical Ultrasound, 2018
Ultrasound (US) is frequently used for evaluating inflammation of subcutaneous tissue caused by pressure ulcers (PUs), but color Doppler mode (CDM) helps to better identify inflammatory edema in subcutaneous fat and necrotic tissue in PUs.
Koichi Yabunaka, Gojiro Nakagami, Tomomitsu Miyagaki, Sanae Sasaki, Chieko Hayashi, Hiromi Sanada   +5 more
doaj   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Traceability of grass feeding in beef: terpenes, 2,3-octanedione and skatole accumulation in adipose tissue of young bulls

Animal, 2011
The development of analytical methods to verify the production system of meat products requires the identification of biomarkers that can trace the product’s origin, and secondly the factors that govern the deposition of these markers in animal tissue ...
E. Serrano, A. Cornu, N. Kondjoyan, J. Agabriel, D. Micol   +4 more
doaj   +1 more source