Results 141 to 150 of about 228,751 (254)

Postoperative intravenous patient‐controlled analgesia improves pain management after subcutaneous implantable defibrillator implantation

open access: yesJournal of Arrhythmia
Objective Postoperative pain is a major issue with subcutaneous implantable cardioverter defibrillators (S‐ICD). In 2020, we introduced intravenous patient‐controlled analgesia (IV‐PCA) in addition to the conventional, request‐based analgesia for ...
Kenta Tsutsui   +16 more
doaj   +1 more source

US Life Expectancy and Increasing Mortality Rates: An Analysis of the Crisis

open access: yesThe Milbank Quarterly, EarlyView.
Policy Points US life expectancy is shorter than in other high‐income countries and the gap has widened dramatically over time, driven in particular by rising mortality rates that threaten the probability that youth can survive to middle age, or even adulthood.
STEVEN H. WOOLF
wiley   +1 more source

Subcutaneous ICD implantation under ultrasound-guided serratus anterior plane block: Single-center experience in the Netherlands. [PDF]

open access: yesInt J Cardiol Heart Vasc, 2022
Elders J   +5 more
europepmc   +1 more source

Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta‐analysis

open access: yesAddiction, EarlyView.
Abstract Background and aims Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment.
Craig Paterson   +13 more
wiley   +1 more source

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu   +10 more
wiley   +1 more source

Tissue Factor‐High Ovarian Clear Cell Carcinoma Shows Immune‐Cold Features and Preclinical Activity of Tisotumab Vedotin

open access: yesCancer Science, EarlyView.
F3/TF‐high ovarian clear cell carcinoma exhibits an immune‐cold phenotype characterized by reduced immune‐cell fractions and attenuated cancer‐cell interferon programs, with frequent B7‐H4 co‐expression. Patient‐derived models show preclinical sensitivity to the TF‐directed antibody–drug conjugate tisotumab vedotin.
Yutaro Mori   +7 more
wiley   +1 more source

Adding Intratumoral Antibody‐Photoabsorber Conjugate Improves Efficacy of Near‐Infrared Photoimmunotherapy (NIR‐PIT)

open access: yesCancer Science, EarlyView.
Intravenous (IV) or intratumoral (IT) cetuximab distribution in A431 tumor (essence of Figure 2). ABSTRACT Near‐infrared photoimmunotherapy (NIR‐PIT) is a new type of cancer treatment that specifically kills target cells while sparing normal tissue. This treatment induces cancer cell death by activating a photoreactive dye with near‐infrared light in ...
Miyu Kano   +9 more
wiley   +1 more source

Subcutaneous ICD–A North Queensland Experience [PDF]

open access: yesHeart, Lung and Circulation, 2017
A. Gupta, R. Park, K. Ng
openaire   +1 more source

Nationwide Lifespan Trends in Cardiac Implantable Electronic Device Strategies in Japan: Age-Dependent Changes in Transvenous and Epicardial Systems. [PDF]

open access: yesJ Arrhythm
Nationwide data revealed age‐dependent differences in CIED implantation strategies. Epicardial systems remain essential in pediatric and congenital heart disease care, whereas alternative technologies are increasingly adopted in older adult populations, reflecting evolving lifespan‐related device strategies.
Miyazaki A   +8 more
europepmc   +2 more sources

Economic burden of hidradenitis suppurativa based on healthcare resource utilization: German claims data analysis

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Hidradenitis suppurativa (HS) is a chronic, debilitating skin disease affecting approximately 0.1% of the German population. Patients with HS require substantial healthcare resource utilization. This study aimed to assess the economic burden associated with HS in Germany.
Falk G. Bechara   +7 more
wiley   +1 more source

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