Results 181 to 190 of about 228,751 (254)

Gastrointestinal adverse effects of GLP‐1 receptor agonists and dual GIP/GLP‐1 receptor agonists: A narrative expert review of approved therapies, oral formulations, and pipeline agents

open access: yesNutrition in Clinical Practice, Volume 41, Issue 5, Page 1318-1333, October 2026.
Abstract Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1 receptor agonists have transformed the management of type 2 diabetes and obesity. Gastrointestinal (GI) adverse events are the most common limitation of these therapies and a leading cause of discontinuation ...
Vikash Singhani   +6 more
wiley   +1 more source

Molecular Engineering Boosts Photon‐Activated Immunotherapy for Prostate Cancer Through Concurrent Pyroptosis and cGAS‐STING Pathway Activation

open access: yesAngewandte Chemie, Volume 138, Issue 39, 21 September 2026.
The engineered DTSe‐based photosensitizer, DZTSe, emerges as an avant‐garde molecular entity, which can distribute to both the endoplasmic reticulum and mitochondria to concurrently trigger pyroptosis and activate the cGAS‐STING pathway. This dual‐action strategy effectively reprograms the tumor microenvironment, enabling potent eradication of primary ...
Cheng Zhang   +7 more
wiley   +2 more sources

Divergent Obesity Classification Between the Edmonton Obesity Staging System and the Lancet Commission Model

open access: yesObesity, Volume 34, Issue 10, Page 1989-1998, October 2026.
ABSTRACT Objective BMI alone does not capture obesity‐related health heterogeneity. The Edmonton Obesity Staging System (EOSS) grades obesity severity based on comorbidities and functional impairment, whereas the Lancet Commission Diagnostic Model for Obesity (DMO) distinguishes preclinical from clinical obesity based on organ dysfunction.
Tobias Hagemann   +3 more
wiley   +1 more source

Device updates successfully reduce T‑wave oversensing and inappropriate shocks in subcutaneous ICD patients. [PDF]

open access: yesNeth Heart J, 2018
Larbig R   +9 more
europepmc   +1 more source

Longitudinal Changes in Transfusion Practice in Myelodysplastic Syndromes: A Population Data‐Linkage Study

open access: yesEuropean Journal of Haematology, Volume 117, Issue 4, Page 1007-1015, October 2026.
ABSTRACT Background Real‐world data on transfusion needs of patients with myelodysplastic syndromes (MDS), and the impacts of disease‐modifying therapies (DMTs) are sparse. In 2011, 5‐azacitidine became the first funded DMT for MDS and chronic myelomonocytic leukaemia (CMML) patients in Australia and national patient blood management (PBM) guidelines ...
Allison Mo   +5 more
wiley   +1 more source

The subcutaneous ICD-current evidence and challenges. [PDF]

open access: yesCardiovasc Diagn Ther, 2014
Patel KH, Lambiase PD.
europepmc   +1 more source

Global Burden of Acne (1990–2021) and Projections for China's Disease Burden Over the Next 15 Years: A Comprehensive Study Based on Global Burden of Disease Data

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Background Acne vulgaris is a common chronic inflammatory skin disease with a significant impact on the global health burden. Although acne vulgaris is more prevalent among adolescents, the incidence of adult acne is gradually increasing, imposing a severe psychological and social burden, particularly on women of reproductive age.
Qian Zhang   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy