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Rats bearing lesions in the septal area followed by lesions in the subfornical organ were submitted to various thirst-eliciting procedures. The rats with hyperdipsia induced by lesions of the septal area drank more water than either during the control ...
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Actions of endothelin at the subfornical organ
Brain Research, 1992Endothelin (ET), a potent vasoconstrictor peptide, is believed to have central sites of action and potential neurohormonal effects relating to body fluid homeostasis and blood-pressure regulation. Systemic endothelin binds to receptors at circumventricular organs and has been shown to increase plasma concentrations of vasopressin and increase the ...
K M, Wall, M, Nasr, A V, Ferguson
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The subfornical organ and carbachol-induced drinking
Brain Research, 1972Summary The initial report of Routtenberg and Simpson 32 indicated that exogenous carbamylcholine chloride (carbachol) applied directly to 3rd ventricle or subfornical organ elicited drinking behavior. The possibility that subfornical organ was the site of action of the carbachol was more thoroughly investigated in this study.
J B, Simpson, A, Routtenberg
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1979
Publisher Summary This chapter discusses the subfornical organ (SFO). SFO is a small, almost hemispherical or ovoid tubercle that protrudes into the lumen of the third ventricle at the level of the interventricular foramina. This topographic relationship is consistent in all vertebrates, regardless of whether the fornix is present or absent, as in ...
H D, Dellmann, J B, Simpson
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Publisher Summary This chapter discusses the subfornical organ (SFO). SFO is a small, almost hemispherical or ovoid tubercle that protrudes into the lumen of the third ventricle at the level of the interventricular foramina. This topographic relationship is consistent in all vertebrates, regardless of whether the fornix is present or absent, as in ...
H D, Dellmann, J B, Simpson
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Timetables of cytogenesis in the rat subfornical organ
Developmental Brain Research, 1990Timetables of neurogenesis and ependymal cell production in the rat subfornical organ (SFO) were determined by examining the offspring of pregnant rats injected with [3H]thymidine on E13-E14, E14-E156, ... E21-E22, respectively. The proportion of postmitotic cells originating each embryonic day was determined by analyzing, in the adult offspring, the ...
E A, Julien, S A, Bayer
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Intrinsic osmosensitivity of subfornical organ neurons
Neuroscience, 2000The constancy of plasma osmolality demands that salt and water concentration within the extracellular fluid be constantly monitored and regulated within a few percentage points. The circumventricular organs in general, and the subfornical organ in particular, have long been proposed to be the site of the osmosensitivity.
J W, Anderson +2 more
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Subfornical organ stimulation elicits drinking
Brain Research Bulletin, 1995The subfornical organ is a specialized central nervous system structure known to be involved in the control of drinking. We report here that electrical activation of subfornical organ neurons (100 microA, 10 Hz, 1 ms pulse width, for 5 min.) induced drinking in 67% (six of nine) of animals.
P M, Smith, R J, Beninger, A V, Ferguson
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Monoamines in the subfornical organ
Brain Research, 1967Abstract The subfornical organ of mouse, rat and cat was investigated by means of the histochemical fluorescence method of Falck and Hillarp for the demonstration of monoamines. Under specific experimental conditions which favor the accumulation of 5-hydroxytryptamine, nerve endings containing this amine can be demonstrated in the mouse throughout ...
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Structure of the subfornical organ: A review
Microscopy Research and Technique, 1998In this review, the light microscopic and fine structural characteristics of neurons, axons, dendrites, glial cells, and capillaries and their topography within the subfornical organ are summarized, with an emphasis on recent findings. Structure-function relationships are discussed whenever possible and put into perspective in a concluding section.
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Cardiovascular Actions of Orexin‐A in the Rat Subfornical Organ
Journal of Neuroendocrinology, 2006Orexin‐A is a neuropeptide, primarily produced in the lateral hypothalamic/perifornical hypothalamus. Orexin receptors and immunoreactive neuronal fibres are widely distributed throughout the brain, suggesting integrative neurotransmitter roles in a variety of physiological systems. Intracerebroventricular injections of orexin‐A increase blood pressure
P M, Smith, W K, Samson, A V, Ferguson
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