Results 111 to 120 of about 11,781 (210)

Reference‐Guided Chromosome‐by‐Chromosome de novo Assembly at Scale Using Low‐Coverage High‐Fidelity Long‐Reads with HiFiCCL

Advanced Science, Volume 13, Issue 13, 3 March 2026.
HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang, Weihua Pan, Runtian Gao, Heng Hu, Wentao Gao, Murong Zhou, Yu‐Hang Yin, Zhipeng Qian, Shuilin Jin, Guohua Wang   +9 more
wiley   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Multi‐View Biomedical Foundation Models for Molecule‐Target and Property Prediction

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Molecular foundation models can provide accurate predictions for a large set of downstream tasks. We develop MMELON, an approach that integrates pre‐trained graph, image, and text foundation models and validate our multi‐view model on over 120 tasks, including GPCR binding.
Parthasarathy Suryanarayanan, Yunguang Qiu, Shreyans Sethi, Diwakar Mahajan, Hongyang Li, Yuxin Yang, Elif Eyigoz, Aldo Guzmán‐Sáenz, Daniel E. Platt, Timothy H. Rumbell, Kenney Ng, Sanjoy Dey, Myson Burch, Bum Chul Kwon, Pablo Meyer, Feixiong Cheng, Jianying Hu, Joseph A. Morrone   +17 more
wiley   +1 more source

SW‐YOLO: An Optimized YOLOv8 Architecture With ConvNeXt for Real‐Time and Accurate Substation Wiring Inspection

Engineering Reports, Volume 8, Issue 3, March 2026.
The study uses affine transformation, contrast enhancement, and mosaic masking for image enhancement and introduces the Convolutional NeXt module in YOLOv8 based on masked self‐encoder and response normalization, along with improvements to the convolutional block attention module.
Yu Lei, Zhihao Liang, Jiayun Huang
wiley   +1 more source

Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries

iMetaOmics, Volume 3, Issue 1, March 2026.
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo, Xiyang Dong, Jia‑Ling Li, Ji‐Cheng Yao, Ziqi Peng, Qi Li, Zi‐Wen Yang, Yang Yuan, Wen‑Jun Li, Pandeng Wang   +9 more
wiley   +1 more source

Perfect Matching Under Precedence Constraints

Networks, Volume 87, Issue 2, Page 175-190, March 2026.
ABSTRACT In this article, we motivate and define variants of perfect matching under precedence constraints where a perfect matching is built incrementally and precedence constraints ensure that an edge may only be added to the matching if the edge's predecessor vertices have already been covered.
Christina Büsing, Corinna Mathwieser
wiley   +1 more source

Qubit‐Efficient Quantum Local Search for Combinatorial Optimization

Advanced Quantum Technologies, Volume 9, Issue 3, March 2026.
We introduce a qubit‐efficient variational quantum algorithm for combinatorial optimization that adaptively uses from logarithmic to a linear number of qubits to implement quantum local search. The method encodes flip probabilities of spin groups into quantum amplitudes, enabling exploration of classically intractable neighborhoods while maintaining ...
Mikhail Podobrii, Viacheslav Kuzmin, Vladimir Voloshinov, Margarita Veshchezerova, Michael R. Perelshtein   +4 more
wiley   +1 more source

Massive Spanning Forests on the Complete Graph: Exact Distribution and Local Limit

Random Structures &Algorithms, Volume 68, Issue 2, March 2026.
ABSTRACT We provide new exact formulas for the distribution of massive spanning forests on the complete graph, which give also a new outlook on the celebrated special case of the uniform spanning tree. As a corollary we identify their local limit. This generalizes a well‐known theorem of Grimmett on the local limit of uniform spanning trees on the ...
Matteo D'Achille, Nathanaël Enriquez, Paul Melotti   +2 more
wiley   +1 more source

Solving a Random Asymmetric TSP Exactly in Quasi‐Polynomial Time W.H.P.

Random Structures &Algorithms, Volume 68, Issue 2, March 2026.
ABSTRACT Let the costs C(i,j)$$ C\left(i,j\right) $$ for an instance of the Asymmetric Traveling Salesperson Problem (ATSP) be independent copies of a nonnegative random variable C$$ C $$ from a class of distributions that include the uniform [0,1]$$ \left[0,1\right] $$ distribution and the exponential mean 1 distribution with mean 1.
Tolson Bell, Alan M. Frieze
wiley   +1 more source

Molecular subgraph representation learning based on spatial structure transformer

Complex & Intelligent Systems
In the field of molecular biology, graph representation learning is crucial for molecular structure analysis. However, challenges arise in recognising functional groups and distinguishing isomers due to a lack of spatial structure information. To address
Shaoguang Zhang, Jianguang Lu, Xianghong Tang   +2 more
doaj   +1 more source