Results 111 to 120 of about 1,516,776 (324)

Stratified analysis of carotid plaque and intima–media thickness as stroke predictors in type 2 diabetes

Frontiers in Endocrinology
BackgroundStroke represents a common macrovascular complication among individuals with type 2 diabetes (T2DM). Carotid intima-media thickness (IMT) and carotid plaque (CP) serve as key indicators of cerebrovascular pathology. However, it is still unclear
Hongmei Fu, Xianwen Wei, Stefan Wirtz
doaj   +1 more source

Incidence of Carpal Tunnel Syndrome Requiring Surgery May Increase in Patients Treated with Trigger Finger Release: A Retrospective Cohort Study

Clinical Epidemiology, 2022
Hsin-Han Hsieh,1 Wen-Tien Wu,1,2 Jui-Tien Shih,3 Jen-Hung Wang,4 Kuang-Ting Yeh1,2 1School of Medicine, Tzu Chi University, Hualien, Taiwan; 2Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan ...
Hsieh HH, Wu WT, Shih JT, Wang JH, Yeh KT   +4 more
doaj  

P3.02b-044 Afatinib versus Gefitinib as First-Line Treatment for EGFR Mutation-Positive NSCLC Patients Aged ≥75 Years: Subgroup Analysis of LUX-Lung 7 [PDF]

, 2017
Keunchil Park, Eng Huat Tan, Li Zhang, Vera Hirsh, Kenneth J. O’Byrne, Michael Boyer, James Chih‐Hsin Yang, Tony Mok, Barbara Peil, Angela Märten, Luis Paz‐Ares   +10 more
openalex   +1 more source

A MULTICENTER RETROSPECTIVE STUDY TO UNDERSTAND THE CLINICAL CHARACTERISTICS FOR PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA: ASIAN SUBGROUP ANALYSIS OF CREEK STUDY [PDF]

, 2023
Bhausaheb Bagal, Chandramouli Nagarajan, Shang‐Ju Wu, Ping Chong Bee, F. Gonzalez, D. H. Shankar   +5 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Risk factors for gastric intraepithelial neoplasia in Chinese adults: a case–control study

Cancer Management and Research, 2018
Yanqiu Yu,1 Cheng Fang,2 Chunyan Peng,3,4 Shanshan Shen,4 Guifang Xu,4 Qi Sun,5 Lin Li,5 Chuan Su,6 Xiaoping Zou3,4 1Department of Gastroenterology, The Affiliated Jiangning Hospital with Nanjing Medical University, Nanjing, People’s Republic of ...
Yu Y, Fang C, Peng C, Shen S, Xu G, Sun Q, Li L, Su C, Zou X   +8 more
doaj  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Supplementary Table 3S from A Randomized Phase II/III Study of Naptumomab Estafenatox + IFNα versus IFNα in Renal Cell Carcinoma: Final Analysis with Baseline Biomarker Subgroup and Trend Analysis

, 2023
Robert E. Hawkins, Martin Gore, Yaroslav Shparyk, Vladimir S. Bondar, Oleg Gladkov, Tosho Ganev, Mihai Hârza, Serhii Polenkov, Igor Bondarenko, Petr Karlov, O. B. Kаryakin, R. Khasanov, Gunnar Hedlund, G. Forsberg, Örjan Nordle, Timothy Eisen   +15 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Basic aspects of meta-analysis. Part 2

Сеченовский вестник
Meta-analysis combines the results of several scientific studies to obtain a summary quantitative estimation of effect size in order to compare the results of several studies and to identify patterns among them and possible sources of biases.
E. A. Tao, M. Yu. Nadinskaia, A. Yu. Suvorov, N. M. Bulanov, V. I. Sholomova, P. P. Potapov, M. S. Taratkin, M. Yu. Brovko   +7 more
doaj   +1 more source