Results 81 to 90 of about 1,516,776 (324)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Adverse Effects of Amoxicillin for Acute Lower Respiratory Tract Infection in Primary Care: Secondary and Subgroup Analysis of a Randomised Clinical Trial

open access: yesAntibiotics, 2017
A European placebo-controlled trial of antibiotic treatment for lower respiratory tract infection (LRTI) conducted in 16 primary care practices networks recruited participants between November 2007 and April 2010, and found adverse events (AEs) occurred ...
Meera Tandan   +7 more
doaj   +1 more source

R chart control limits based on a small number of subgroups technical report no. 83 [PDF]

open access: yes
Statistical analysis - R chart control limit based on small number of ...
Hillier, F. S.
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Using a Gaussian Graphical Model to Explore Relationships Between Items and Variables in Environmental Psychology Research

open access: yesFrontiers in Psychology, 2019
Exploratory analyses are an important first step in psychological research, particularly in problem-based research where various variables are often included from multiple theoretical perspectives not studied together in combination before.
Nitin Bhushan   +5 more
doaj   +1 more source

Stratigraphic columns and correlations for the Late Eocene - Oligocene Te Kuiti Group, central-western North Island, New Zealand [PDF]

open access: yes, 2008
This report presents a compilation of stratigraphic columns for geological sections and outcrops of Late Eocene – Oligocene Te Kuiti Group units in central-western parts of North Island, New Zealand, between Port Waikato and Awakino.
Kamp, Peter J.J.   +2 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Heterogeneity between subgroups of first-line chemoimmunotherapy for extensive-stage small cell lung cancer patients: a meta-analysis and systematic review

open access: yesFrontiers in Oncology
ObjectivesDifferences in clinicopathological characteristics of extensive-stage small cell lung cancer (ES-SCLC) patients may influence the immune response.
Wenwen Kang   +7 more
doaj   +1 more source

Triad Census and Subgroup Analysis of Patient-Sharing Physician Collaborations

open access: yesIEEE Access, 2018
The collaboration among physicians during episodes of care for hospitalized patients makes a significant contribution to effective health outcomes. Although physician collaborations are frequently analyzed to explore their impact on healthcare outcomes ...
Shahadat Uddin   +2 more
doaj   +1 more source

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