Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Exploratory study of non-ordinary states of consciousness during sleep show distinct electrophysiological features from wakefulness and canonical sleep stages. [PDF]
Sci RepHerrero NL +4 more
europepmc +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Local variations in L/M ratio influence the detection and color naming of small spots. [PDF]
J VisGreene MJ +3 more
europepmc +1 more source
Psychiatric Disability and Employment: II.Follow-Up of 95 Unemployed Subjects [PDF]
, 1955 Morris Markowe +2 more
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
XLIV. An abstract of a memoir on physical geology; with a further exposition of certain points connected with the subject [PDF]
W. John Hopkins
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A Virus Neutralization Test, Subject to Standardization: Used with Western Equine Encephalomyelitis, St. Louis Encephalitis and Mouse-Adapted Poliomyelitis Viruses [PDF]
, 1942 William McDowell Hammon, E. M. Izumi
openalex +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Cross-Subject EEG Emotion Recognition Using SSA-EMS Algorithm for Feature Extraction. [PDF]
Entropy (Basel)Lu Y, Chen J.
europepmc +1 more source