Results 101 to 110 of about 72,911 (291)

Relevance of Subject Descriptions in an Online Public Access Catalogue

open access: yesKnjižnica: revija za področje bibliotekarstva in informacijske znanosti, 2013
ABSTRACTPurpose:  The aim of the article is to identify the relevance of subject headings in the online library catalogue (OPAC) and to verify the hypothesis that the database structure and the search language is more in favour of natural and technology sciences researchers than to researchers in the field of humanities.
openaire   +2 more sources

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

open access: yesAdvanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang   +16 more
wiley   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

open access: yesAdvanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang   +8 more
wiley   +1 more source

Preserving newspapers: National and international cooperative efforts [PDF]

open access: yes, 1991
Historians have always turned to newspapers to see how events were interpreted at the time that they occurred. Now, more than ever, with an increased interest in social history and in the daily life of the common person, historians have come to ...
Swartzburg, Susan Garrison
core  

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

open access: yesAdvanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He   +10 more
wiley   +1 more source

Innovative's Electronic Resource Management as catalyst for change at Glasgow University Library [PDF]

open access: yes, 2006
In March 2003 Glasgow University Library joined with Innovative and several other Innovative customers to develop a new Electronic Resource Management (ERM) module.
Galloway, L.
core  

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

open access: yesAdvanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun   +19 more
wiley   +1 more source

Design and Implementation of an Aligned Domain Knowledge Graph for Academic Taxonomies

open access: yesSukkur IBA Journal of Computing and Mathematical Sciences
This research paper details the design and implementation of an Aligned Domain Knowledge Graph, focusing on constructing a subject-based taxonomy for academic disciplines. The primary objective is to enhance information retrieval tasks, such as indexing,
Rida Sara   +5 more
doaj   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

open access: yesAdvanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl   +27 more
wiley   +1 more source

Interoperable subject retrieval in a distributed multi-scheme environment : new developments in the HILT project [PDF]

open access: yes, 2005
The HILT (HIgh-Level Thesaurus) project (http://hilt.cdlr.strath.ac.uk/), based primarily at the Centre for Digital Library Research (CDLR) (http://cdlr.strath.ac.uk/) at Strathclyde University in Glasgow is entering its fourth stage following the ...
McCulloch, E., Nicholson, D.
core   +1 more source

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