Results 101 to 110 of about 196,069 (314)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Une séance d’histoire au Cycle 3

open access: yesLidil, 2007
A history lesson in cycle 3 (keystage 2): the teacher’s enunciative posture in the mediation between documents and pupilsThe article consists in the analysis of an ordinary history lesson in keystage 2: the collective exploitation of iconographic ...
Anne Leclaire-Halté
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Assisting reading and analysis of text documents by visualization

open access: yes, 2005
The research reported here examined the use of computer generated graphics as a means to assist humans to analyse text documents which have not been subject to markup.
Maloney, Ross J.
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Some core concepts of domain analysis

open access: yesEm Questão
This article claims that information systems should provide reliable and trustworthy information, and that this demand imply a re-orientation of information science with knowledge organization from, for example, approaches based on ...
Birger Hjørland
doaj   +1 more source

Walking football for older adults: Systematic review

open access: yesE-balonmano.com: Revista de Ciencias del Deporte, 2021
The study aims to conduct a systematic review based on the results found around the Walking football, in order to know the sport rules and the benefits of it practice for health and general well-being in older adults.
José M. Gamonales   +5 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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