Results 111 to 120 of about 6,945,689 (299)
The subject of enunciation, conceived as the construction of discourse, that is, as the meaning effect of individuality, implies a voice, a body, a character and an "ethos".
Norma Discini
doaj
WAYS OF EXPRESSING THE SUBJECT IN THE AVAR LANGUAGE
This article is devoted to the ways of expressing the subject in the Avar language, in which case word forms expressing subjective actions are singled out as the subject. In the Avar language, the subject, predicate and direct object form the basis of a three-part sentence of transitional semantics and a two-part sentence of intransitive semantics. The
openaire +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
THE THEOLOGICAL EXPRESSION IN ADELIA PRADO´S POETIC LANGUAGE: LYRICAL SUBJECT RELATIONS WITH GOD
Research about the questions about the human experience and its relation with the sacred expressed in 13 poemas of Adélia Prado a brazilian writer. After the reading of the poems were created 5 categories to analizes: the love for God, the distance of ...
Marco Antonio Palermo Moretto
doaj
Male rhesus monkeys (n = 24) had a biopsy of prefrontal cortical area 46 prior to chronic ethanol self-administration (n = 17) or caloric control (n = 7). Fourteen months of daily self-administration (water vs.
Robert Hitzemann +21 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

