Results 111 to 120 of about 400,752 (311)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Improving and expanding Medical Subject Headings (MeSH) during times of social change

open access: yesThe International Journal of Information, Diversity, & Inclusion
In the summer of 2020, the Latinx Caucus of the Medical Library Association focused on addressing bias in medical subject heading terminologies by establishing the Hispanic/Latinx Inclusive Terminologies Project. Two project teams were formed.
Aidy Weeks   +2 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

THE DATABASE OF THE AUTHORITATIVE FILE „SUBJECT HEADINGS” IS AN IMPORTANT COMPONENT OF INTEGRATION OF THE EDUCATIONAL LIBRARIES

open access: yesІнформаційні технології і засоби навчання, 2014
The article is focused on the problem of creating a database of the authoritative file of thematic subject headings concerning education, pedagogy and psychology in the electronic catalogue at V.
Nataliia Ye. Zorina
doaj  

A Glossary of Index Headings, pp. xxxv-xlviii [PDF]

open access: yes, 1944
The Catherwood Library and ILR School at Cornell are pleased to again make available an extremely important index of major labor union publications, long out of print. It is Lloyd G. Reynolds and Charles C.
Killingsworth, Charles C   +1 more
core   +1 more source

New Frontiers In Collection Development Preparing To Meet New Standards

open access: yes, 2004
This article describes the general policies which may be included in a comprehensive collection development policy, attempting to follow national guidelines. It also describes one approach to analyzing how well the library collection supports the various
Shook, Gary R.
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

MeSH Medical Subject Headings

open access: yes, 2023
MesH es Sistema de Organización de Conocimiento digital  que tiene papel protagónico en la organización y recuperación de información científica y de mayor impacto en las biociencias. En el vasto, diverso y complejo mundo de la literatura científica, el Medical Subject Headings (MeSH) de PubMed actúa como un guía, permitiendo a los investigadores ...
openaire   +1 more source

Costing study of two-year accelerated honours degrees [PDF]

open access: yes, 2011
Report to HEFCE by Liz Hart Associates. "[This] study had two key objectives: to provide evidence of the impact of two-year accelerated honours degrees on course costs; to make comparisons with the costs of comparable degrees delivered through the ...
Foster, Will, Hart, Liz, Lewis, Tony
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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